Now showing items 1-2 of 2
Residual Bootstrap Test for Interactions in Biomarker Threshold Models with Survival Data
Many new treatments in cancer clinical trials tend to benefit a subset of patients more. To avoid unnecessary therapies and failure to recognize beneficial treatments, biomarker threshold models are often used to identify ...
Bayesian inference for treatment-biomarker interaction in clinical trials
Some baseline patient factors, such as biomarkers, are useful in predicting patients’ responses to a new therapy. Identification of such factors is important in enhancing treatment outcomes, avoiding potentially toxic ...