Now showing items 1-3 of 3
RET Mediated Gene Expression and Cell-Migration
The RET receptor tyrosine kinase is important during development of neural crest-derived tissues, particularly the enteric and sympathetic nervous systems, and in kidney morphogenesis. Activation of RET requires complex ...
A Role for Fer in Prostate and Breast Cancer
Phosphorylation of substrates by kinase proteins is one of the most prominent mechanisms by which signal transduction occurs and dysregulation of this activity is implicated as a major underlying cause of a number of ...
Identification and characterization of ΔNp63 as a novel transcriptional target negatively regulated by TAZ in mammary tumorigenesis
The transcriptional co-activator with PDZ-binding domain (TAZ) is a key downstream component of the Hippo pathway that plays important roles in animal size control, stem cell renewal, differentiation and tumorigenesis. We ...