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The Ezrin Signalling Network as a Potential Novel Marker in Breast Cancer Metastasis
Metastasis is the leading cause of mortality in human breast cancer. However, there are few predictive, prognostic, or therapeutic targets of breast cancer metastasis. Ezrin, a membrane cytoskeletal cross-linker, is ...
Automated Quantification and Clinical Implications of Src, Ezrin, and Tks5 in Breast Cancer
Breast cancer (BC) is one of the leading causes of cancer-related deaths in Canadian women. Aggressive BCs (e.g. triple-negative subtype; TN) present a clinical challenge as defined biomarkers, particularly those indicative ...
A Novel Regulatory Role of Ezrin in Promoting Breast Cancer Cell Invasion and Metastasis
Metastasis is the leading cause of death for breast cancer patients and poses significant clinical challenges in the successful treatment of breast cancer. The cytoskeleton crosslinker protein ezrin, is frequently ...