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The Influence of Sequence Variation on von Willebrand Factor Biosynthesis, Proteolytic Processing and Clearance
Von Willebrand factor (VWF) promotes platelet adhesion and aggregation at sites of vascular damage. This function is directly related to the multimer size of VWF. The VWF-specific metalloprotease ADAMTS13 decreases VWF ...
The Thrombogenic Influences of Factor VIII and von Willebrand Factor
von Willebrand factor (VWF) and factor VIII (FVIII) circulate in the blood as a non-covalent complex. VWF plays an important role in primary hemostasis through its interactions with components of the extracellular matrix ...