Browsing by Subject "vitamin D"
Now showing items 1-4 of 4
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Functional studies of the human 25-hydroxyvitamin D3-24-hydroxylase, CYP24A1
(2015-07-29)This thesis focuses on the cytochrome P450 CYP24A1, which catabolizes 1α,25-dihydroxyvitamin D3 (1α,25-(OH)2D3) via two pathways commencing with C24-, or C23-hydroxylation and culminating in calcitroic acid or 1α,25-(OH) ... -
The role of vitamin D signalling in the interaction between mesenchymal mammary tumour cells and macrophages
(2016-09-01)The transition of epithelial-like tumour cells to those exhibiting mesenchymal characteristics (Epithelial-to-mesenchymal Transition; EMT) is an integral process in breast cancer metastasis. EMT can be promoted by Transforming ... -
Vitamin D and mammographic density in postmenopausal women: A cohort study nested within a chemoprevention trial
(2014-03-31)Background: Vitamin D may be important in the causal pathway to breast cancer (BC) by influencing mammographic breast density (MD). However, previous study results in postmenopausal women are inconsistent. Study objectives ... -
Vitamin D status in winter and summer among nurses and implications for cancer etiology
(2009-09-23)Background: Recent research indicates that inadequate vitamin D status may incur increased cancer risk, particularly for breast and colon cancer. Cutaneous generation of vitamin D through direct absorption of summer sunlight ...