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Now showing items 4904-4923 of 13430
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Functional and Physiological Determinants of Perceived Disability in Individuals Diagnosed with Osteoarthritis of the Hip
(2016-04-06)Objectives: The main objective of this pilot study was to investigate which standardized functional and physiological test best predicted perceived disability in a single group of 21 individuals diagnosed with osteoarthritis ... -
Functional and physiological measures in individuals with hip osteoarthritis
(2008-09-27)Background: Osteoarthritis of the hip joint causes difficulties to the elderly because it impacts their ability to conduct their normal activities of daily living, such as walking, cooking, bathing, dressing, using the ... -
Functional characterization of a Kar3/Vik1-like Kinesin-14 heterodimer from the filamentous multinucleate fungus Ashbya gossypii
(2012-07-30)Kinesins are motor proteins that convert chemical energy from ATP hydrolysis into mechanical energy used to generate force along microtubules, transporting organelles, vesicles, and proteins within the cell. Kar3 kinesins ... -
Functional Characterization of Human ADCK3 and ADCK4, Mitochondrial Atypical Kinases
(2015-11-20)AarF domain containing kinases 3 and 4 (ADCK3 and ADCK4, respectively) are paralogous human mitochondrial proteins, co-orthologs of the yeast protein Coq8 and bacterial protein UbiB. These proteins are required in the ... -
The functional characterization of klp-20/vab-6: A gene encoding a kinesin-like protein required for Caenorhabditis elegans embryonic morphogenesis
Motor proteins convert chemical energy to perform mechanical work which cells require for essential activities, such as transporting cargo away from the nucleus. Kinesins are one class of molecular motors which cells use ... -
Functional Characterization of TAFI mutants Resistant to Activation by Thrombin, Thrombin-Thrombomodulin or Plasmin
(2009-02-03)Thrombin-activatable fibrinolysis inhibitor (TAFI) is a human plasma zymogen that acts as a molecular link between the coagulation and fibrinolytic cascades. TAFI can be activated by thrombin and plasmin but the reaction ... -
Functional Characterization of Teleost Intrinsic Photosensitive Dermal Chromatophores
(2013-08-27)Mammalians process their photoreceptions through lateral eyes; however, non-mammalian vertebrates and invertebrates possess additional extraretinal photoreceptors over their bodies to detect light stimuli. Chromatophores, ... -
Functional Chemometrics: Automated Spectral Smoothing with Spatially Adaptive Splines
(2012-10-02)Functional data analysis (FDA) is a demonstrably effective, practical, and powerful method of data analysis, yet it remains virtually unheard of outside of academic circles and has almost no exposure to industry. FDA adds ... -
Functional consequences of the direct physical interaction between E2A transcription factors and CBP/p300
(2007-10-01)The E2A locus is involved in chromosomal translocations associated with acute lymphoblastic leukemia. The most common of these involves a translocation between chromosomes 1 and 19 (t1;19), resulting in expression of the ... -
Functional Diversity in Colour Vision of Fish
(2012-05-14)The overall objective of this thesis was to understand better the mechanisms that shape the diversity in colour vision of fish, and to explore the adaptive significance of this divergence. Among the vertebrates, teleost ... -
Functional Interrogation of microRNA-375 in Merkel Cell Carcinoma
(2013-08-15)Merkel cell carcinoma (MCC) is a rare but highly aggressive neuroendocrine cutaneous cancer whose molecular biology is poorly characterized. Our broad research objective is to identify microRNAs (miRNA) that are biologically ... -
Functional Magnetic Resonance Imaging of Pain in the Spinal Cord and Brainstem
(2008-09-26)Functional magnetic resonance imaging (fMRI) studies performed to date have focused on brain structures rostral to the thalamus, although the first level of sensory information and pain transmission occurs at the spinal ... -
Functional Magnetic Resonance Imaging of Peripheral Neuropathic Pain in the Spinal Cord and Brainstem
(2010-08-06)To date, most studies investigating the neural signature of pain in humans have focused on the brain, and those studies concerned with more caudal areas (such as the spinal cord (SC) or brainstem) have used only experimental ... -
Functional Nitroxyls in Polypropylene Based Thermoplastic Vulcanizates
Peroxide vulcanization of polypropylene (PP) based thermoplastic vulcanizates (TPVs) is hindered by PP’s susceptibility to radical degradation. PP degradation occurs through chain scission of tertiary alkyl macroradicals, ... -
Functional Rehabilitation Criteria Required for a Safe Return to Active Duty in Military Personnel Following a Musculoskeletal Injury
(2016-04-05)The objective of this article is to assess the types of musculoskeletal (MSK) injuries commonly affecting military personnel and the outcome measures that may be used to predict a safe return to active duty post-injury. ... -
Functional size traits in crowded vegetation: when bigger isn’t better
Why do some species within crowded vegetation have greater numerical abundance than others? Functional traits are often explored as predictors of success under certain habitat conditions, and in the context of competition, ... -
Functional studies of the human 25-hydroxyvitamin D3-24-hydroxylase, CYP24A1
(2015-07-29)This thesis focuses on the cytochrome P450 CYP24A1, which catabolizes 1α,25-dihydroxyvitamin D3 (1α,25-(OH)2D3) via two pathways commencing with C24-, or C23-hydroxylation and culminating in calcitroic acid or 1α,25-(OH) ... -
A FUNCTIONAL, COMPARATIVE AND CLINICAL ANALYSIS OF SPERM-BORNE OOCYTE ACTIVATING FACTOR, PAWP
(2013-10-01)Successful fertilization depends upon the activation of metaphase II arrested oocytes by sperm-borne oocyte activating factor (SOAF). Failure of oocyte activation is considered as the cause of treatment failure in a ... -
Functionality based refactoring : improving source code comprehension
(2008-01-02)Software maintenance is the lifecycle activity that consumes the greatest amount of resources. Maintenance is a difficult task because of the size of software systems. Much of the time spent on maintenance is spent trying ... -
FUNCTIONALIZED-NITROXYLS FOR USE IN PEROXIDE-INITIATED MODIFICATIONS OF POLYMERS
(2014-09-17)Delayed-onset crosslinking of commodity polymers is accomplished by peroxide-initiated reactions of 4-acryloyloxy-2,2,6,6,-tetramethylpiperidine-N-oxyl (AOTEMPO) under solvent-free conditions. Consistent with previous ...