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Now showing items 4999-5018 of 13430
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Genetic Suppression of Stress Sensitivity Following Loss of SSPI (CAMKK) in Schizosaccharomyces Pombe
(2014-01-27)Loss of the ssp1 protein kinase (CAMKK) gene results in stress sensitivity, cell elongation, slow growth and in some cases cell cycle arrest. In order to identify new components of the ssp1 stress response pathway, a ... -
Genetic variation in vitamin D-related genes among European and East Asian women and risk of breast cancer and risk according to breast tumour subtypes
(2015-09-12)Vitamin D is hypothesized to decrease breast cancer risk by controlling cell proliferation, differentiation and apoptosis, and estrogen synthesis and signalling in breast tissue. Transport of circulating vitamin D to sites ... -
Genocidio, La Cosa Nostra: Uncovering Theories of Individual Responsibility for Collective International Crimes
(2015-01-21)The purpose of this study is to examine the dilemma of how individual criminal responsibility can be attributed, in a principled manner, for crimes that have been perpetrated through collective conduct within the context ... -
GENOMIC CHARACTERIZATION OF RECURRENT CHROMOSOMAL ABERRATIONS IN RETINOBLASTOMA
(2010-10-19)Retinoblastoma is the second most common childhood intraocular malignancy and development of the tumour is initiated by bi-allelic loss of the RB1 gene. Bi-allelic RB1 loss may not always directly lead to malignant ... -
Genomic Consequences of Mating System Evolution in the Pacific Coastal Dune Endemic, Abronia Umbellata (Nyctaginaceae)
(2016-09-06)The advent of next-generation sequencing has significantly reduced the cost of obtaining large-scale genetic resources, opening the door for genomic studies of non-model but ecologically interesting species. The shift in ... -
The genomic consequences of sexual selection
(2012-01-26)Sex-differences in phenotype, development, and life-history can alter the strength of selection experienced by males and females. In particular, theoretical models have demonstrated that differences in the strength of ... -
Genomic Rearrangements in Autism Spectrum Disorders: Identification of Novel Candidate Genes
(2009-11-23)There is evidence from family studies for the importance of genetic factors in the development of autism spectrum disorders (ASDs) but the identification of major genes has not been achieved to date. There are several ... -
Genotypic Differences and Life-History Trade-Offs in the Freshwater Zooplankton, Daphnia Pulicaria, Under Natural Levels of Food Limitation
(2011-08-15)The schedule of growth, reproduction and survivorship of an individual are the key components of life history, which reflect fitness performance of a genotype. Examining the variation in life history performance among ... -
The Gentleman-Scholar at Home: Domesticity, Masculinity, and Civility in Dutch Seventeenth-Century Genre Painting
(2016-10-01)This dissertation examines the gentleman-scholar depicted at home in Dutch seventeenth-century genre paintings, focusing primarily on art created in the Northern Netherlands from the 1630s through the 1670s. The methodological ... -
GEOCHEMICAL AND MICROBIAL ASSESSMENT OF THE UNCONFORMITY-RELATED URANIUM PROSPECTIVITY OF THE HAWK RAPIDS AREA, SOUTHEASTERN ATHABASCA BASIN, CANADA
(2014-08-18)Hawk Rapids is a uranium exploration project located in the southeastern part of the Athabasca Basin, in Saskatchewan, Canada. Geochemical and mineralogical assessments of drill core from Hawk Rapids were used to evaluate ... -
THE GEOCHEMICAL AND MINERALOGICAL CONTROLS ON THE ENVIRONMENTAL MOBILITY OF RARE EARTH ELEMENTS FROM TAILINGS, NECHALACHO DEPOSIT, NORTHWEST TERRITORIES
(2014-05-28)Increased demand for rare earth elements (REEs) for applications in modern technologies has led to an increase in REE exploration. Several deposits are expected to begin mining within a decade, but few studies have examined ... -
GEOCHEMICAL AND MINERALOGICAL EVOLUTION OF THE MCARTHUR RIVER ZONE 4 UNCONFORMITY-RELATED URANIUM ORE BODY AND APPLICATION OF IRON OXIDATION STATE IN CLAY ALTERATION AS INDICATOR OF URANIUM MINERALIZATION
(2012-11-05)The sandstone-hosted McArthur River Zone 4 U ore body and alteration system, located in the Athabasca Basin, are the focus of a detailed mineralogical and geochemical study aimed at reconstructing its evolution. The ... -
Geochemical Characterization of Coexisting Precipitates and Waters from High-Sulfidation Epithermal Gold Deposits
(2016-02-03)Water management and treatment at closed mine sites have become primary concerns for mining companies due to their costly nature, potential commitment of decades of water treatment, and impact on the environment. The ... -
GEOCHEMICAL EVALUATION OF LIVING AND HOLOCENE BRACHIOPODS AND THE RELATIONSHIP WITH MODERN OCEANOGRAPHY, SOUTHERN AUSTRALIAN SHELF
(2015-10-01)Brachiopod shell chemistry is a commonly used proxy in paleoceanography and paleoclimate studies because their shells are composed of diagenetically-resistant low-Mg calcite and are, for the most part, in chemical equilibrium ... -
GEOCHEMICAL INDICATORS OF BURIED SULPHIDE MINERALISATION UNDER SEDIMENTARY COVER NEAR TALBOT LAKE, MANITOBA
(2011-05-16)The Paleoproterozoic Talbot volcanogenic massive sulphide (VMS) Cu-Zn occurrence is located near Talbot Lake, Manitoba, about 80 km south of Snow Lake. The mineralised system is unconformably overlain by more than 100 m ... -
Geodesic reduction via frame bundle geometry
(2007-07-25)Reduction theory for systems with symmetry deals with the problem of understanding dynamics on a manifold with an action of a Lie group. In geometric mechanics, this problem can be formulated in the Lagrangian, Hamiltonian ...