Browsing by Author "6e18ada9ef06d65fcc758e452a74aabf"
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Biological Control of Potato Common Scab With Rare Isatropolone C Compound Produced by Plant Growth Promoting Streptomyces A1RT
Sarwar, Arslan; Latif, Zakia; Zhang, Songya; Zhu, Jing; Zechel, David; Bechthold, Andreas (Frontiers, 2018-05-30)Potato is prone to many drastic diseases like potato common scab (CS). As no highly effective methods exist for managing CS, this study explored the possibility of using biological control. Ten bacterial strains were ... -
Identification of Genes Essential for Sulfamate and Fluorine Incorporation During Nucleocidin Biosynthesis
Pasternak, Ola; Bechthold, Andreas; Zechel, David (Wiley, 2022-05-11)Nucleocidin is an adenosine derivative containing 4’-fluoro and 5’-O-sulfamoyl substituents. In this study, nucleocidin biosynthesis is examined in two newly discovered producers, Streptomyces virens B-24331 and Streptomyces ... -
Role of Two Exceptional trans Adenylation Domains and MbtH-like Proteins in the Biosynthesis of the Nonribosomal Peptide WS9324A from Streptomyces calvus ATCC 13382
Bernhardt, Mirjam; Berman, Stefanie; Zechel, David; Bechthold, Andreas (Chemistry Europe - European Chemical Societies Publishing, 2020-04-25)Nonribosomal peptide synthetases (NRPS) are organized in a modular arrangement. Usually, the modular order corresponds to the assembly of the amino acids in the respective peptide, following the collinearity rule. The ... -
Secondary Nucleotide Messenger C-Di-GMP Exerts a Global Control on Natural Product Biosynthesis in Streptomycetes
Makitrynskyy, Roman; Tsypik, Olga; Nuzzo, Desiree; Paululat, Thomas; Zechel, David; Bechthold, Andreas (Oxford Academic, 2020-01-16)Cyclic dimeric 3′-5′ guanosine monophosphate, c-di-GMP, is a ubiquitous second messenger controlling diverse cellular processes in bacteria. In streptomycetes, c-di-GMP plays a crucial role in a complex morphological ...