Early pregnancy is characterized by complex interactions between blood vessels, leukocytes, and conceptus-derived trophoblasts within the gestational uterus. Uterine Natural Killer (uNK) cells become the most abundant ...

Endometriosis affects 5-10% of women and is characterized by the growth of endometrial tissue outside of the uterus. Treatment for endometriosis primarily focuses on symptom relief, is short term with severe side effects ...

Preeclampsia (PE) is a significant gestational disorder affecting 3-5% of all human pregnancies. In many PE pregnancies, maternal plasma is low in the placentally-produced angiokine “placental growth factor” (PGF). Offspring ...

Endometriosis, characterized by the growth of endometrium outside the uterine cavity, is a disease which causes pelvic pain, inflammation and associated with infertility. Endometrium, which exits the uterus through retrograde ...

Endometriosis is a debilitating gynecological disease characterized by the presence of endometrial-like tissue lesions outside of the uterus. Chronic inflammation is a hallmark feature of endometriosis, which has been ...

Preeclampsia (PE) is a multisystem disorder of pregnancy, characterized by new onset hypertension and the presence of specific organ dysfunction such as proteinuria. While the etiology remains elusive, it is believed to ...

Angiogenesis, the growth of blood vessels from pre-existing vascular structures, can contribute adaptively or mal-adaptively to a myriad of conditions, including ischemic heart disease and cancer. During angiogenic sprouting, ...

Heme degradation is catalyzed through the action of heme oxygenases (HO), present as inducible (HO-1) and constitutive (HO-2) isoforms, resulting in the endogenous production of carbon monoxide (CO), biliverdin and iron. ...

Endometriosis is a gynecological disease defined as the growth of endometrium outside of the uterus. Although linked to 50% of female infertility cases, current medical treatments fail to maintain fecundity. Since the ...

Numerous studies have identified that elevated plasma concentrations of lipoprotein(a) [Lp(a)] are an emerging risk factor for a variety of atherothrombotic disorders. Apolipoprotein(a) [apo(a)], the unique glycoprotein ...