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Investigating the role of reactive oxygen species in transplacental benzene carcinogenesis
The incidence of childhood leukemia is increasing, especially in urbanized areas. It is hypothesised that transplacental exposure to environmental carcinogens, such as benzene, plays a role in the etiology of childhood ...
The effects of 1,4-benzoquinone on c-Myb and topoisomerase II in K-562 cells
Exposure to benzene, a ubiquitous environmental pollutant, has been linked to leukemogenesis, although the mechanism of benzene initiated carcinogenesis remains unclear. It has been proposed that benzene can be bioactivated ...
Investigating benzene-initiated DNA double-strand breaks and recombination after acute and in utero exposure in mice
Benzene is an ubiquitous pollutant and industrial solvent that has been identified as a human leukemogen. Early exposure to environmental carcinogens such as benzene has been postulated to play a role in the etiology of ...