Browsing Graduate Theses, Dissertations and Projects by Author "Taha, Zaid"

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Effect of Oncogenes Upon the Signal Transducer and Activator of Transcription-3 (Stat3) and the Dominant-Negative Isoform Stat3β

Taha, Zaid

Stat3 is activated by cytokine receptors and non-receptor kinases and plays an etiological role in neoplasia. Stat3 activation entails phosphorylation at the tyrosine 705 residue (Y705), dimerization through a reciprocal ...