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Characterization of Glucocorticoid Receptor Promoter Methylation in Breast Cancer
Epidemiological studies have identified psychological stress as a significant risk factor in breast cancer. The stress response is regulated by the HPA axis in the brain and is mediated by glucocorticoid receptor (GR) ...
Validation of a Gene-Expression Based Assay for BRCA1 Function
Breast cancer is a disease that afflicts a significant proportion of women globally. 5-10% of breast cancer cases are linked to inherited polymorphisms in critical genes such as BRCA1, a tumour suppressor essential for ...
Association between Use of a Specialized Diagnostic Assessment Unit and the Diagnostic Interval in Ontario Breast Cancer Patients
Background: The amount of time that it takes to get a breast cancer diagnosis is very important to patients. The Ontario diagnostic assessment unit (DAU) is designed to improve the quality and timeliness of care during a ...