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Targeting the actin cytoskeleton in HER2+ metastatic cancer cells using a macrolide toxin
Breast and ovarian cancers are among the leading causes of cancer related deaths in women worldwide. In a subset of these cancers, dysregulation of the human epidermal growth factor receptor 2 (HER2) leads to overexpression ...
The Role of Endocytic Adaptor Endophilin A2 in Human Breast Cancer Signaling, Metastasis, and Targeted Therapy
The leading cause of death in breast cancer is metastatic burden. Classification of breast cancer cases by molecular subtype reveals that those categorized as triple-negative (TNBC) and human epidermal growth factor receptor ...