Now showing items 1-4 of 4
Regulation of the Gene Encoding Thrombin-Activable Fibrinolysis Inhibitor in Non-Hepatic Cells
Thrombin-activable fibrinolysis inhibitor (TAFI) is a carboxypeptidase B-like pro-enzyme that, once activated, attenuates fibrinolysis. TAFIa also possesses anti-inflammatory properties. Although liver is the main source ...
The effect of biomechanical and biochemical regulators on the expression of Factor VIII and von Willebrand Factor in endothelial cells
The coagulant protein Factor VIII (FVIII) has been the subject of much debate and controversy regarding where, when, and how it is expressed and produced in the human body for much of the past 30-40 years. Expression was ...
The response of the murine sensory nervous system to augmented levels of colonic nerve growth factor
The primary goal of this research is to understand the response of the tyrosine receptor kinase A (trkA)-expressing cells of the myenteric plexus, and dorsal root ganglia (DRG) to augmented levels of nerve growth factor ...
Effects of Increased Inflammation on Antiviral CD8+ T Cell Responses in Mice Overexpressing the Human-Cysteinyl Leukotriene 2 Receptor (hCysLT2R)
Inflammation plays a vital role in promoting naïve cytotoxic T lymphocyte (CD8+ T cell) differentiation. Infection with lymphocytic choriomeningitis virus (LCMV) elicits a robust CD8+ T cell response in the mouse. Cysteinyl ...