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Selective serotonin reuptake inhibitors (SSRIs) and breast cancer : a record linkage study
Evidence suggests that selective serotonin reuptake inhibitors (SSRIs, a class of antidepressant medications) may contribute to increased breast cancer risk by stimulating the secretion of prolactin, a potential tumour ...
Communicating Results of New Genomic Tests to Physicians
Background: New genomic tests are being developed to predict an individual’s risk of cancer recurrence by analyzing the expression of multiple genes. However, it is unclear how to report the test results so that they would ...
Molecular Stress Signaling in Breast Epithelial Cells
Breast cancer is a complex disease, whose etiology is not well understood. A number of factors have been found to contribute to its development. Psychological stress has been recognized as such a factor in epidemiological ...
ROLE OF CELL ADHESION MICROENVIRONMENT AND THE SRC/STAT3 AXIS IN AUTOCRINE HGF SIGNALING DURING BREAST TUMOURIGENESIS
Over-expression of both hepatocyte growth factor (HGF) and its receptor Met frequently occurs in invasive human breast cancer, suggesting that the establishment of an HGF “autocrine loop” may be linked to breast tumour ...
THE MAMMARY EPITHELIAL CELL-SPECIFIC ROLE OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR)γ IN DMBA-MEDIATED BREAST TUMOURIGENESIS
Breast cancer is the most commonly diagnosed cancer, and the second leading cause of cancer-related deaths, among women world-wide. Improved understanding of breast tumourigenesis may facilitate the development of more ...