Graduate Theses, Dissertations and Projects: Recent submissions
Now showing items 1-20 of 6048
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Exploring Epigenetic Drug Discovery Using Computational Approaches
The misregulation of epigenetic mechanisms has been linked to disease. Current drugs that treat these dysfunctions have had some success, however many have variable potency, instability in vivo and lack target specificity. ... -
Characterization of Strain Rate Sensitivity, Plastic Anisotropy, and Dislocation Content in Zircaloy-2
Zirconium alloys are used broadly throughout the nuclear industry due to a combination of its mechanical properties, low neutron absorption cross section, and resistance to corrosion. Understanding the process of plastic ... -
A Secure Keyless Entry System Based on Contextual Information
Proximity identification has been widely used in access control systems. These systems, in particular Passive Keyless Entry and Start systems (PKES) for high-end automobiles, allow drivers to unlock their vehicles by ... -
Page or Stage: Reading Shakespeare Comics as Performance
While previous scholarship concerning Shakespeare comics has considered their pedagogical function as teaching tools to make Shakespeare more accessible or their role in preserving Shakespeare’s place within the popular ... -
Mode I Fracture Testing on Zirconium Foils Under Plane-stress Condition
Zirconium alloys are commonly used in nuclear reactor in-core components due to their good mechanical properties and low neutron-absorption cross-section. Especially for CANada Deuterium Uranium (CANDU) reactors, zirconium ... -
Is Daoism Green? Engaging Daoist Responses to Environmental Challenges in China
This paper seeks to examine the role that Daoism is playing in environmental activism in China. It analyzes a variety of sources including academic literature, primary source material from Daoist groups and my own research ... -
Neural Processing in Primary Motor Cortex and its Relationship to Contralateral and Ipsilateral Motor Actions
The role of primary motor cortex (M1) in controlling movements has been a long-debated subject because M1 neurons have been shown to relate to many different aspects of motor control. A confounding issue is that different ... -
Polymeric Ionic Liquid Compositions for In-Situ Product Removal Bioreactor Applications
Although the biosynthesis of n-butanol and succinic acid can afford renewable fuels, solvents, and chemical intermediates, these bioprocesses suffer from the cytotoxicity of their end products, leading to reduced production ... -
"It's Just a Sport. It's Just a Sport, Right?": The Reproduction of Class Privilege in Ultimate
Invented in 1968, Ultimate is a self-officiating, non-contact, team sport played with a flying disc. Over the course of the past 50 years, Ultimate has rapidly gained popularity and is often cited as being among the fastest ... -
An evaluation of hyaluronic acid and poly-L-lysine polyelectrolyte layers on alginate microspheres for use in protein-triggered drug release
Age-related macular degeneration (AMD) is the leading cause of vision loss in developed countries in those 50 years of age and older. Increased expression of the protein vascular endothelial growth factor (VEGF) plays a ... -
Investigation of Hydroisomerization Catalysts and Reaction Conditions to produce Branched-Chain Fatty Acids
Fatty acids (FAs) from vegetable oils can be used as feed to produce renewable hydrocarbons and bio-lubricants. Naturally occurring FAs are, however, susceptible to oxidative attack and have operating temperature limitations ... -
Differential Contributions of RET-isoforms to Tumour Invasion
RET is a receptor tyrosine kinase (RTK) which is normally activated at the cell surface by glial cell line-derived neurotrophic factors and plays critical roles during embryogenesis. RET is expressed as two protein isoforms, ... -
Investigating Selenium Usage Challenges and Reducing the Performance Overhead of Selenium-based Load Tests
Selenium automates the testing of web applications. Quality Assurance (QA) engineers usually write Selenium scripts to test the content that is rendered in a browser and simulate user interactions with the web content for ... -
Assessing the Geographic and Socioeconomic Determinants of Private Well Water Testing Practices in Southern Ontario
Purpose: An estimated 4.3 million Canadians use private wells for daily water consumption, however well testing rates are declining, potentially resulting in an increased risk of exposure to groundwater contaminants ... -
Second Place at the Polish Pow Wow
Abstract This paper begins with an Indigenous buffalo teaching. It is followed by aspects of my own story of Métis cultural rediscovery. My hope is this will provide insight into why I am undertaking this writing, as well ... -
Revisiting the Nature of Transformational Leadership: How Followers' Affect Matters
The seven studies within this dissertation investigate the nature of transformational leadership. I consider whether transformational leadership is affective, whether it is multidimensional, and whether people perceive ... -
Advances in 5-(Hydroxymethyl)Furfural Production From Cellulose Via CO2-Catalysis
The global economy must make a radical shift to lower carbon emissions to avert large-scale impacts from climate change. Fuels derived from widely available biomass such as macroalgae, have the potential to limit the CO2 ... -
Optical Visualization of Two Phase Flow in PEM Electrolyzers
Polymer electrolyte membrane (PEM) electrolyzers are ideally suited to pairing with renewable energy sources given the capability to operate at high current densities and transition between different potential loading. ... -
Mechanisms of Social Cognition in Early Episode Psychosis
The mental abilities required to identify, understand, and respond to social information are broadly referred to as social cognition, and individuals with schizophrenia spectrum disorders display significant impairments ... -
Electrochemical Water Oxidation by Heterogenized Iridium-NHC Precatalyst
Hydrogen production from water splitting provides a potential source for clean energy storage. However, this process requires catalysts that can oxidize water to provide a source of electrons for proton reduction. Various ...