Browsing Pathology and Molecular Medicine, Department of by Author "Tryggvason, Karl"

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The scavenger receptor SCARA5 is an endocytic receptor for von Willebrand factor expressed by littoral cells in the human spleen

Swystun, Laura L.; Ogiwara, Kenichi; Lai, Jesse D.; Ojala, Juha R. M.; Rawley, Orla; Lassalle, Fanny; Notley, Colleen; Rengby, Olle; Michels, Alison; Nesbitt, Kate; Tryggvason, Karl; Lillicrap, David (Wiley, 2019-05-24)

Background Scavenger receptors play a significant role in clearing aged proteins from the plasma, including the large glycoprotein coagulation factors von Willebrand factor (VWF) and factor VIII (FVIII). A large genome-wide ...