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The Experience of the Older Adult With End-Stage Renal Disease on Hemodialysis
(2011-09-15)
Background: The growth in the number of individuals with end-stage renal disease has implications in terms of both the health of individuals, especially older adults (aged 65 years and older), and the capacity of the health ...
Adopting Obligations: Duties to Existing Children
(2012-09-10)
This thesis argues that infertile prospective parents have a moral obligation to adopt rather than pursue ARTs (Assisted Reproductive Technology). The first chapter presents the negative argument against the common desire ...
Design and implementation of an analyzer for a timed pi-calculus
(2010-09-29)
In this thesis, we design and implement an analysis tool for a language called kiltera which is a timed extension of pi-calculus. kiltera allows the modeling of concurrent, mobile, real-time and distributed systems. Our ...
Tracing Flows of Water, Energy, and Waste Through an Idealized Water Distribution Network Using an Urban Metabolism Based Approach
(2015-09-03)
‘Urban Metabolism’ (UM) is a well-established concept based on the parallels between the metabolisms’ of ecosystems and cities. These parallels consist of the intake, storage, and transformation of materials and energy, ...
Homo and hetero-dimerization studies of two Zn(II)2Cys6 transcription factors in fission yeast
(2012-07-06)
This thesis presents a strategy designed to determine how Thi1 and Thi5 may differentially regulate thiamine production and the vegetative and sexual life cycles in fission yeast. Fission yeast cells regulate the cell ...
The Acute Effects of Ambient Temperature Exposure on Mental Illness Related Emergency Room Visits in the City of Toronto
(2013-05-27)
Objectives: The purpose of this study was to assess the effects of extreme ambient temperature on hospital emergency room (ER) visits related to mental and behavior disorders in Toronto, Canada.
Methods: A time series ...
Seafloor Massive Sulphides: Assessment of Sustainable Mining Potential through an Iterative Decision-making Framework
(2011-12-12)
Extraction of metals from the seafloor has been considered for decades, beginning with manganese nodules in the 1970s. Today, the targets are massive sulphide deposits rich in copper, zinc, gold, and silver that are ...
Comparison of Pyramidal and Magnocellular Neuroendocrine Cell Volume Responses to Osmotic Stress and Stroke - Like Stress
(2011-02-14)
Acute brain cell swelling (cytotoxic edema) can occur in the first minutes of stroke, presumably as a result of brain cells taking up water. In extreme hypo-osmotic situations such as excessive water-loading by patients, ...
Elucidating the interaction between the Fragment 2 domain of Prothrombin and Factor Va
(2012-08-03)
The prothrombinase (IIase) complex is an essential component of the coagulation cascade and is composed of a serine protease, Factor Xa (FXa), its non-enzymatic cofactor, Factor Va (FVa), calcium and a phospholipid membrane ...
Melancholy and the Early Modern University
(2011-09-27)
Critics have observed that in early Stuart England, the broad, socially significant concept of melancholy was recoded as a specifically medical phenomenon—a disease rather than a fashion. This recoding made melancholy seem ...