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REGULATORY DOMAINS OF THE HUMAN CALPAIN FAMILY
Calpains are intracellular enzymes that merge cysteine protease and calcium sensing activities together in one molecule. They respond to Ca2+ signals and modify the activity of their targets by selective proteolysis. ...
REGULATION OF CALPAIN 2 BY CALPASTATIN
Calpains are a family of intracellular cysteine proteases activated by calcium. They participate in many processes including cell motility, cell cycle progression and cell death, in response to calcium signaling. Because ...
CALPAIN 2 ACTIVATION, AUTOLYSIS, AND SUBUNIT DISSOCIATION
Calpains are calcium-dependent, intracellular, multi-domain cysteine proteases involved in many physiological functions regulated by calcium signaling, including cell motility. How calpains are activated in the cell is ...