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The Unliganded Glucocorticoid Receptor as a Transcriptional Regulator in Mammary Epithelial Cells
This work presents the first evidence of a ligand-independent role for the glucocorticoid receptor (GR) as a positive regulator of gene expression in mammary cells. We have demonstrated that unliganded GR interacts directly ...
Regulation of the GABPβ Promoter and the Role of NRF-1 in Mammary Epithelial Morphogenesis
Decreased expression of the tumor suppressor gene BRCA1 (breast cancer 1, early onset) is frequently observed in sporadic breast tumors, with the decrease not attributed to mutations or hypermethylation of the promoter. A ...