• Endothelial cell synthesis of Factor VIII 

      Riches, Jonathan Jacob (2013-03-13)
      Factor VIII (FVIII) is an essential blood-clotting protein and mutations in the FVIII gene are the cause of hemophilia A, a severe inherited bleeding disorder. FVIII synthesis has been observed in discreet endothelial ...
    • FVIII Immunity : early events and tolerance mechanisms to FVIII 

      Qadura, Mohammad Imad (2008-08-15)
      Among the complications of current treatments for hemophilia A, the development of anti-FVIII antibodies including “FVIII inhibitors” remains the major clinical problem in treating hemophiliacs. Factor VIII inhibitors work ...