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    • Browsing Department of Pathology and Molecular Medicine Graduate Theses by Subject
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    • Pathology and Molecular Medicine, Department of
    • Department of Pathology and Molecular Medicine Graduate Theses
    • Browsing Department of Pathology and Molecular Medicine Graduate Theses by Subject
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    Browsing Department of Pathology and Molecular Medicine Graduate Theses by Subject "Variants of Unknown Significance"

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      • Characterization of Variants of Unknown Significance (VUS) in BRCA1 

        Kim, Daniel
        Approximately 3%-8% of breast cancer patients carry one defective BRCA1 or BRCA2 allele. While the rise of genetic testing have helped identify BRCA mutation carriers, the implication of certain mutations are still unknown. ...
      • Validation of a Gene-Expression Based Assay for BRCA1 Function 

        Uy, Paolo Miguel (2013-09-26)
        Breast cancer is a disease that afflicts a significant proportion of women globally. 5-10% of breast cancer cases are linked to inherited polymorphisms in critical genes such as BRCA1, a tumour suppressor essential for ...

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