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The Ezrin Signalling Network as a Potential Novel Marker in Breast Cancer Metastasis
Metastasis is the leading cause of mortality in human breast cancer. However, there are few predictive, prognostic, or therapeutic targets of breast cancer metastasis. Ezrin, a membrane cytoskeletal cross-linker, is ...
A Novel Regulatory Role of Ezrin in Promoting Breast Cancer Cell Invasion and Metastasis
Metastasis is the leading cause of death for breast cancer patients and poses significant clinical challenges in the successful treatment of breast cancer. The cytoskeleton crosslinker protein ezrin, is frequently ...
The role of PPARg-dependent microRNA expression during breast tumour metastasis
Previous studies by Dr. Nicol showed the first direct in vivo evidence that peroxisome proliferator-activated receptor (PPAR)γ normally suppresses environmental chemical 7,12-dimethylbenz[a]anthracene (DMBA)-mediated breast ...