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Fabrication of a Bioactive Scaffold Material for Meniscus Tissue Engineering
(2013-11-20)
Injuries to the meniscus are a common and important source of mobility issues in the knees of young active individuals, as well as elderly individuals. Conventional treatments for these injuries involve surgical resections ...
Optimization and Biological Characterization of Decellularized Adipose Tissue Scaffolds for Soft Tissue Reconstruction
(2014-01-30)
It would be a great advantage in reconstructive surgery to have an off-the-shelf biomaterial to promote regeneration and volume augmentation following soft tissue damage. With this long-term objective, human adipose tissue ...
Development of a Microinjection Platform for the Examination of Host-Biomaterial Interactions in Zebrafish Embryos
Current approaches in biomaterial development require a series of in vitro and in vivo assays to identify and optimize candidate materials. Current in vitro assays have low labor requirements and are relatively cheap ...
Aqueous Cu(0) Mediated Reversible Deactivation Radical Polymerization of 2-Hydroxyethyl Acrylate
(2015-08-31)
Reversible deactivation radical polymerization (RDRP) of 2-hydroxyethyl acrylate in D2O was studied using Cu(0) wire and Me6TREN, with different target chain lengths (TCL), amount of initial Cu(II)Br2, and the addition ...
Matrix-Derived Microcarriers for Adipose Tissue Engineering
(2010-12-01)
In vivo, adipose tissue demonstrates only a limited capacity for self-repair, and the long-term treatment of subcutaneous defects remains an unresolved clinical problem. With the goal of regenerating healthy tissues, many ...
Modulating the Inflammatory Response of Macrophages on Biomaterial Surfaces
The foreign body response is an inflammatory response to implanted materials and poses significant challenges for biomaterials-based medical applications, often leading to the degradation or fibrous encapsulation of an ...