Browsing Department of Chemical Engineering Graduate Theses by Title
Now showing items 158-177 of 276
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Matrix-Derived Microcarriers for Adipose Tissue Engineering
(2010-12-01)In vivo, adipose tissue demonstrates only a limited capacity for self-repair, and the long-term treatment of subcutaneous defects remains an unresolved clinical problem. With the goal of regenerating healthy tissues, many ... -
A Mean-Squared-Error-Based Methodology for Parameter Ranking and Selection to Obtain Accurate Model Predictions at Key Operating Conditions
(2015-01-06)In this thesis, a new mean-squared-error (MSE)-based criterion, rCCW, is proposed to select the optimal number of parameters to estimate from the ranked list of parameters considering the operating region where accurate ... -
Measurement System Design for Chemical Processes
(2011-06-16)The problem of measurement system design for stochastic linear systems, a popular modeling strategy for chemical processes, is addressed. A multi-objective optimization approach is used. The design metrics are the capital ... -
Mechanistic Studies of Radical-mediated Polyolefin Modifications
(2009-01-12)The free radical addition of saturated polymers and small molecules to unsaturated monomers is used to prepare functional derivatives under solvent-free, reactive extrusion conditions. Of particular interest are the dynamics ... -
Medium-Chain-Length Poly (3-Hydroxyalkanoate) Nanoparticle Suspensions
(2016-08-18)The main goal of this thesis was to prepare medium-chain-length poly-3-hydroxyalkanoate (mcl-PHA) nanoparticle suspensions at high solids content (≥ 10 % w/v). A two-stage emulsification-solvent evaporation process was ... -
Membrane Electrode Assembly Fabrication and Test Method Development for a Novel Thermally Regenerative Fuel Cell
(2012-10-13)A test system for the performance analysis of a novel thermally regenerative fuel cell (TRFC) using propiophenone and hydrogen as the oxidant and fuel respectively was designed and built. The test system is capable of ... -
A Method to Improve Cartilage Integration
(2009-12-23)One major barrier that prevents cartilage integration following mosaic arthroplasty is the presence of a zone of chondrocyte death (ZCD) that is generated upon osteochondral graft harvest, which can extend up to 400 μm ... -
Micro/Nanoencapsulation of Proteins Within Alginate/Chitosan Matrix by Spray Drying
(2007-11-02)Currently, therapeutic proteins and peptides are delivered subcutaneously, as they are readily denatured in the acidic, protease rich environment of the stomach or gastrointestinal track and low bioavailability results ... -
Model Development and Parameter Estimation for Styrene Polymerization
(2012-02-22)A model is developed to describe the bulk thermally-initiated free-radical polymerization of styrene between 100 °C and 170 °C. This model incorporates a comprehensive thermal initiation mechanism including generation and ... -
Model-Based Optimal Design of Experiments with Noninvertible Fisher Information Matrix
In this thesis, different approaches are developed and compared to deal with a noninvertible Fisher Information Matrix (FIM) when designing sequential model-based (e.g., A, D, and V-optimal) experiments. Proposed approaches ... -
Modeling and Development of Three-Dimensional Gel Dosimeters
(2014-03-27)A dynamic mathematical model was developed to simulate the response of polyacrylamide gel (PAG) dosimeters to a single spherical radioactive brachytherapy seed. Simulations were conducted for a high dose-rate (HDR) seed ... -
Modeling of Molecular Weight Distributions in Ziegler-Natta Catalyzed Ethylene Copolymerizations
(2009-05-29)The objective of this work is to develop mathematical models to predict molecular weight distributions (MWDs) of ethylene copolymers produced in an industrial gas-phase reactor using a Ziegler-Natta (Z-N) catalyst. Because ... -
Modeling of pCO2 Point-of-Care Devices
(2014-02-06)A dynamic model is developed and presented that predicts the voltage response for a Severinghaus electrode-based point-of-care pCO2 sensor. Eight partial differential equations are derived to describe the diffusion and ... -
Modeling the Thermal Stability of in vitro Diagnostic Bioassays
(2011-02-02)The objective of this work is to develop mathematical models for predicting the thermal stability of commercial diagnostic assays. These assays are a product of the Point of Care division of Abbott laboratories, and are ... -
Modelling the Concentration Distribution of Non-Buoyant Aerosols Released from Transient Point Sources into the Atmosphere
(2007-10-23)Neural network models were developed to model the short-term concentration distribution of aerosols released from point sources. Those models were based on data from a wide range field experiments (November 2002, March, ... -
Modification of a High-Temperature Electrochemical Testing Station and Experimental Development for Solid Oxide Electrolysis Cell Anode Analysis
(2016-01-27)A method to fabricate solid oxide electrolysis cell (SOEC) anodes in a controlled process has been developed. Adjustment of deposition rate was found to alter the anode porosity and particle size distribution. A solid oxide ... -
Modification of Alginate and Development of Polymeric Nanocarriers by Living Radical Polymerization for Controlled/Targeted Drug Delivery
(2015-12-03)Alginate-based amphiphilic graft copolymers were synthesized by single electron transfer living radical polymerization (SET-LRP), forming stable micelles during polymerization induced self-assembly (PISA). First, alginate ... -
Modification of Poly(methyl methacrylate) Surfaces with Azobenzene Groups to Develop a Photoresponsive Surface
Photoswitchable surfaces can be used to reversibly control surface wettability, adsorptivity, and protein adhesion to influence cell interactions at the surface. Control over protein adsorption and cell adhesion is useful ... -
Modification of Polysaccharides and their Use as Pickering Emulsifiers in Oil/Water Emulsions, Miniemulsion, and Microsuspension Polymerization
Emulsion and suspension systems are the basis for the formulation of a wide variety of products including pharmaceuticals, consumables such as food, personal care or cosmetics and commodity materials such as adhesives, ... -
The Modification, Design and Development of a Scaled-down Industrial Furnace with Interchanging Burners for Academic Use
(2010-07-19)Industry is heavily dependent on the process of combustion and with a projected rapid increase for the demand of combustion-derived energy it is imperative to expose a new age of engineering professionals to the discipline ...