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Chronic prenatal ethanol exposure produces neurobehavioural and metabolic dysfunction in guinea pig offspring
Maternal ethanol consumption during pregnancy can produce teratogenic outcomes in offspring, which are collectively termed Fetal Alcohol Spectrum Disorder (FASD). Central nervous system (CNS) dysfunction is a debilitating ...
ACTIVATION OF HEME OXYGENASE-2 TO IMPROVE OUTCOME AFTER TRAUMATIC BRAIN INJURY
Traumatic brain injury (TBI) is an injury of the brain most often caused by blunt force trauma to the head and typically characterized by an increase in reactive oxygen species (ROS), inflammation, and hemorrhaging. Heme ...
The impact of cAMP signalling on the dynamics of endothelial tubule formation
Signalling mediated by the ubiquitous cellular messenger cyclic adenosine monophosphate (cAMP) plays a central role in numerous cellular processes. Within vascular endothelial cells (VECs), cAMP signalling influences ...
EXAMINING ALTERED NF-κB SIGNALLING FOLLOWING 1,4- BENZOQUINONE EXPOSURE IN HD3 CELLS
In utero exposure to benzene, a known environmental contaminant, is associated with increased risk of childhood leukemia. We have previously shown that in utero benzene exposure can alter the redox sensitive transcription ...