Now showing items 1-2 of 2
NOVEL AZOLE-BASED HEME OXYGENASE INHIBITORS: IN VIVO CHARACTERIZATION AND THERAPEUTIC APPLICATION IN CANCER
Heme degradation is catalyzed through the action of heme oxygenases (HO), present as inducible (HO-1) and constitutive (HO-2) isoforms, resulting in the endogenous production of carbon monoxide (CO), biliverdin and iron. ...
Impacts of Placental Growth Factor Deficiency and of Preeclampsia on Brain Development and Function
Preeclampsia (PE) is a significant gestational disorder affecting 3-5% of all human pregnancies. In many PE pregnancies, maternal plasma is low in the placentally-produced angiokine “placental growth factor” (PGF). Offspring ...