Now showing items 1-5 of 5
Characterization of the MexT Regulator of the mexEF-oprN Multidrug Efflux Operon of Pseudomonas aeruginosa
Pseudomonas aeruginosa is resistant to many clinically-relevant antibiotics and this is partly attributable to multidrug efflux systems in this organism. One of these, MexEF-OprN, exports chloramphenicol, fluoroquinolones ...
The Role of Neu1 Sialidase in Epidermal Growth Factor Receptor Activation
The epidermal growth factor receptor (EGFR) exists as a single, highly glycosylated subunit receptor on the plasma membrane of a cell. Upon ligand binding to its extracellular domain, the EGFR dimerizes with an adjacent ...
Characterization of the Baculovirus Late Expression Factor-3 Oligomerization Interaction Domains Using Protein Complementation Assay
Late expression factor 3 is one of the six AcMNPV genes essential for DNA replication identified through transient replication assays. LEF-3 is a single stranded DNA binding protein responsible for the transportation of ...
Lipopolysaccharide-Mediated Regulation of IL-17 Receptor Levels in Human Monocytes
IL-17 promotes inflammation through the recruitment of monocytes and induction of various chemokines and inflammatory cytokines. Monocytes respond to IL-17 through the heteromeric IL-17 receptor (IL-17R) composed of ...
Elucidation of Protein‐Protein Interactions in the Flagella Structure and Characterization of the Glycosylation State of Flagellin Subunits of the Methanogenic Archaeon Methanococcus Maripaludis
The archaeal flagellum is a rotating prokaryotic motility apparatus used for swimming motility and adhesion; however, it is more closely related to the bacterial type IV pilus system than its bacterial namesake. Methanococcus ...