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CHARACTERIZATION OF THE BACULOVIRUS LATE EXPRESSION FACTOR-3 OLIGOMERIZATION INTERACTION DOMAINS USING PROTEIN COMPLEMENTATION ASSAY
Late expression factor 3 is one of the six AcMNPV genes essential for DNA replication identified through transient replication assays. LEF-3 is a single stranded DNA binding protein responsible for the transportation of ...
Lipopolysaccharide-Mediated Regulation of IL-17 Receptor Levels in Human Monocytes
IL-17 promotes inflammation through the recruitment of monocytes and induction of various chemokines and inflammatory cytokines. Monocytes respond to IL-17 through the heteromeric IL-17 receptor (IL-17R) composed of ...
The Role of Neu1 Sialidase in Epidermal Growth Factor Receptor Activation
The epidermal growth factor receptor (EGFR) exists as a single, highly glycosylated subunit receptor on the plasma membrane of a cell. Upon ligand binding to its extracellular domain, the EGFR dimerizes with an adjacent ...
Characterization of the MexT Regulator of the mexEF-oprN Multidrug Efflux Operon of Pseudomonas aeruginosa
Pseudomonas aeruginosa is resistant to many clinically-relevant antibiotics and this is partly attributable to multidrug efflux systems in this organism. One of these, MexEF-OprN, exports chloramphenicol, fluoroquinolones ...
ELUCIDATION OF PROTEIN‐PROTEIN INTERACTIONS IN THE FLAGELLA STRUCTURE AND CHARACTERIZATION OF THE GLYCOSYLATION STATE OF FLAGELLIN SUBUNITS OF THE METHANOGENIC ARCHAEON METHANOCOCCUS MARIPALUDIS.
The archaeal flagellum is a rotating prokaryotic motility apparatus used for swimming motility and adhesion; however, it is more closely related to the bacterial type IV pilus system than its bacterial namesake. Methanococcus ...