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Investigating Antigen Presentation by Inactivated Lymphocytic Choriomeningitis Virus and by Baculovirus Encoding the LCMV-Nucleoprotein
Professional antigen presenting cells (pAPCs) process and present antigens on their cell surface in association with MHC class I molecules through two general pathways: direct or cross-presentation. The process of antigen ...
CHARACTERIZATION OF THE BACULOVIRUS LATE EXPRESSION FACTOR-3 OLIGOMERIZATION INTERACTION DOMAINS USING PROTEIN COMPLEMENTATION ASSAY
Late expression factor 3 is one of the six AcMNPV genes essential for DNA replication identified through transient replication assays. LEF-3 is a single stranded DNA binding protein responsible for the transportation of ...
CHARACTERIZING THE FUNCTIONAL DOMAINS OF THE BACULOVIRUS LATE EXPRESSION FACTOR 3 (LEF-3) INVOLVED IN NUCLEAR LOCALIZATION AND DNA REPLICATION
Transient replication assays have identified a late expression factor 3, LEF-3, to be essential for DNA replication and late gene expression in the baculovirus species, AcMNPV. Although its specific role in these two ...
Characterization of the interactions of baculovirus transcription and replication regulators by bimolecular fluorescence complementation
Baculovirus gene expression is temporally divided into early and late stages. Viral late expression factors (LEFs) are essential for the transition between the early and late transcriptional stages, as well as for late ...