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Regulation of the mexAB-oprM efflux operon of Pseudomonas aeruginosa
Multidrug efflux systems are important determinants of antimicrobial resistance in the human pathogen Pseudomonas aeruginosa where they compromise anti-pseudomonal chemotherapy. The major multidrug efflux system in P. ...
The mexCD-oprJ multidrug efflux operon in Pseudomonas aeruginosa: regulation by the NfxB-like novel regulator PA4596 and envelope stress
Expression of the mexCD-oprJ multidrug efflux operon is enhanced by the presence of membrane damaging agents [e.g., the biocide chlorhexidine (Chx)] or mutations in the nfxB gene encoding a repressor of efflux gene expression, ...