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dc.contributor.authorSikka, Rituen
dc.date2013-09-16 12:38:10.757
dc.date.accessioned2013-09-16T19:46:47Z
dc.date.available2013-09-16T19:46:47Z
dc.date.issued2013-09-16
dc.identifier.urihttp://hdl.handle.net/1974/8284
dc.descriptionThesis (Master, Neuroscience Studies) -- Queen's University, 2013-09-16 12:38:10.757en
dc.description.abstractWe investigated age-related differences in neural activation associated with recognition of familiar melodies, a process that requires retrieval from musical semantic memory and leads to a feeling of familiarity. We used sparse sampling fMRI to determine the neural correlates of melody processing and familiarity by comparing activation when listening to melodies versus signal-correlated noise, and to familiar versus unfamiliar melodies, respectively. Overall, activity in the bilateral superior temporal gyrus correlated well with melody processing. Familiarity was associated with several frontal regions (bilateral inferior frontal gyrus, superior frontal gyrus, and precentral gyrus; left insular cortex), right superior temporal gyrus; left supramarginal gyrus and cingulate gyrus; bilateral putamen and thalamus; cerebellum and brainstem. No significant differences were found between younger and older adults for either melody processing or familiarity based activation. Assessment of familiarity-related group differences using less stringent criteria identified plausible areas; greater activation was seen bilaterally in the superior temporal gyrus in younger adults and in some left parietal regions in older adults. This study adds to the knowledge of musical semantic memory with results based on a large sample (N = 40) that includes older adults. Our findings for activation associated with melody processing and familiarity support some, but not all, previous results of related studies. We were unable to find conclusive evidence of age-related differences in neural correlates of musical semantic memory, while also being the first study (to the best of our knowledge) to search for these differences.en
dc.language.isoengen
dc.relation.ispartofseriesCanadian thesesen
dc.rightsThis publication is made available by the authority of the copyright owner solely for the purpose of private study and research and may not be copied or reproduced except as permitted by the copyright laws without written authority from the copyright owner.en
dc.subjectmusical semantic memoryen
dc.subjectsparse samplingen
dc.subjectfMRIen
dc.subjectmusical memoryen
dc.subjectmelody processingen
dc.subjectsuperior temporal gyrusen
dc.subjectneural basis of musical memoryen
dc.subjectinferior frontal gyrusen
dc.subjecteffects of aging on musical semantic memoryen
dc.subjectmusical lexiconen
dc.subjectagingen
dc.subjectfamiliarityen
dc.subjectfamiliar melodiesen
dc.subjectsemantic memoryen
dc.subjectrecognitionen
dc.titleAn fMRI comparison between younger and older adults of neural activity associated with recognition of familiar melodiesen
dc.typethesisen
dc.description.degreeM.Sc.en
dc.contributor.supervisorCuddy, Lola L.en
dc.contributor.supervisorJohnsrude, Ingrid S.en
dc.contributor.departmentNeuroscience Studiesen
dc.degree.grantorQueen's University at Kingstonen


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