Detection Limits of Chemical Sensors: Applications and Misapplications

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Authors

Loock, Hans-Peter
Wentzell, Peter D.

Date

2016-03-08

Type

journal article

Language

en

Keyword

Limit of Detection , Sensitivity , Calibration Curve , Confidence Interval , Fiber Optic Sensors , Photoacoustic Sensor , Absorption Sensor , Refractive Index Sensor

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Abstract

The limit of detection (LOD) and the sensitivity of a chemical sensor are defined using IUPAC guidelines. The LOD from simulated and experimental data is calculated from a calibration curve using a simple statistical model that was implemented into a spreadsheet program. This definition of the LOD is compared with the commonly used definition of the LOD, which is based on the product of sensitivity and the theoretical instrument resolution.

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