Browsing Biomedical and Molecular Sciences, Department of by Title
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Zinc exposure increases resistance to polymyxins in Pseudomonas aeruginosa through activation of the arn operon and two-component regulatory systems
Metal cations have long been known to play a role in driving antibiotic resistance. The metal cation Zn2+ has previously been shown to drive antibiotic resistance in various bacterial species, including the opportunistic ... -
β-Arrestin-Mediated Regulation of the Human Ether-a-go-go-Related Gene (hERG) Potassium Channel
(2016-09-06)The human ether-a-go-go-related gene (hERG) encodes the voltage-gated K+ channel, hERG (Kv11.1). This channel passes the rapidly-activating delayed rectifier K+ current (IKr), which is important for cardiac repolarization. ...