Now showing items 1-10 of 105
The Relationship between Hospital Infection Surveillance and Control Activities and Antibiotic Resistant Pathogen Rates
Objective: The purpose of the study was to examine the relationship of surveillance and control activities in Canadian hospitals with rates of nosocomial methicillin-resistant S. aureus (MRSA), C. difficile associated ...
Studies of Coagulation and Fibrinolysis
The mechanism and regulation of prothrombinase function in the activation of prothrombin and prethrombin-1 were studied. In addition, the kinetics of plasmin-mediated fibrin degredation were determined. First, the mechanism ...
Investigating the role of reactive oxygen species in transplacental benzene carcinogenesis
The incidence of childhood leukemia is increasing, especially in urbanized areas. It is hypothesised that transplacental exposure to environmental carcinogens, such as benzene, plays a role in the etiology of childhood ...
The Role of Lipoprotein(a)/Apolipoprotein(a) in Endothelial Dysfunction: Mechanistic Studies in Vascular Endothelium
Multiple lines of evidence suggest that elevated plasma lipoprotein(a) (Lp(a)) concentrations are a significant risk factor for the development of a number of vascular diseases including coronary heart disease and stroke. ...
Regulatory Domains of the Human Calpain Family
Calpains are intracellular enzymes that merge cysteine protease and calcium sensing activities together in one molecule. They respond to Ca2+ signals and modify the activity of their targets by selective proteolysis. ...
Genomic Rearrangements in Autism Spectrum Disorders: Identification of Novel Candidate Genes
There is evidence from family studies for the importance of genetic factors in the development of autism spectrum disorders (ASDs) but the identification of major genes has not been achieved to date. There are several ...
Effects of Apolipoprotein(a) on Vascular Endothelial Cell Function: Insights Into Possible Physiological and/or Pathological Roles for Lipoprotein(a)
Numerous studies have identified that elevated plasma concentrations of lipoprotein(a) [Lp(a)] are an emerging risk factor for a variety of atherothrombotic disorders. Apolipoprotein(a) [apo(a)], the unique glycoprotein ...
Axotomized Spinal Commissural Interneurons of the Adult Feline: A study of axonal growth from dendrites and cut axons
Acquiring knowledge of the morphological, molecular, and functional changes that occur to neurons following axotomy is a key step for a comprehensive understanding of the nervous system and how it reacts to injury. ...