Browsing Neuroscience Studies (CNS), Centre for by Publish Date
Now showing items 21-40 of 269
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The Prevalence of Epilepsy and Seizures in Subjects with Fetal Alcohol Spectrum Disorders
(2009-07-23)The Prevalence of Epilepsy and Seizures in Subjects with Fetal Alcohol Spectrum Disorders. MSc Thesis, Queen’s University, Kingston, Ontario, Canada, May 2009. OBJECTIVE: Fetal alcohol spectrum disorders (FASD) is the ... -
Anoxia-Induced Changes in Action Potential Propagation in a Non-Myelinated Axon
(2009-08-13)Processing information in the nervous system is energetically expensive, constraining the ability of the system to survive disturbances caused by stress. While some organisms compensate for extreme changes in the abiotic ... -
An Investigation of Sleep Architecture and Consequent Cognitive Changes in Olanzapine Treated Patients with Depression
(2009-09-10)Objective: Primarily, to determine the effect of olanzapine augmentation therapy on sleep architecture, specifically slow wave sleep (SWS), in the treatment of depression. Secondarily, to determine the effect of olanzapine ... -
Sexual Responses in the Human Spinal Cord
(2009-10-07)Altered sexual function is one of the most devastating consequences of spinal cord trauma (SCT). Despite this fact, current knowledge of the neural circuitry regulating sexual response in the spinal cord (SC) in healthy ... -
The Effect of Training on Haptic Classification of Facial Expressions of Emotion in 2D Displays by Sighted and Blind Observers
(2009-10-23)Abstract The current study evaluated the effects of training on the haptic classification of culturally universal facial expressions of emotion as depicted in simple 2D raised-line drawings. Blindfolded sighted (N = 60) ... -
The Role of Rapid Eye Movement and Slow Wave Sleep for the Consolidation of Memory in Rats
(2009-10-26)The functions of sleep remain enigmatic. One of the dominant, yet more contentious hypotheses is that sleep is involved in memory consolidation. A large body of evidence supports the role of rapid eye movement (REM) sleep ... -
Coordinating the eyes and hand in goal-directed movement sequences
(2009-11-13)Coordinated gaze and hand movements predominate a number of our interactions in reachable space and yet few studies examine the potential contribution of tactile feedback in planning these actions. This thesis was designed ... -
The Activation of Persistent Inward Currents in Feline Spinal Motoneurons is Noise and Location-Dependent
(2009-12-07)The ability to control the output for a given input is an important feature of neurons as it allows them to respond to a multitude of inputs via the production of a scalable output. Using compartmental models of morphologically ... -
Neural correlates of focused attention in cognitively normal older adults, patients with mild cognitive impairment and patients with mild Alzheimer's disease
(2010-01-05)Impaired attention can hinder information processing at multiple levels and may explain some aspects of the cognitive decline in aging. An inefficient inhibitory system can lead to deficits in focused attention (FA). FA ... -
Children With Alcohol-Related Neurodevelopmental Disorder or Attention Deficit/Hyperactivity Disorder Differ on Neuropsychological Tasks and Measures of Eye Movement Control
(2010-01-18)Children with alcohol-related neurodevelopmental disorder or attention deficit/hyperactivity disorder differ on neuropsychological tasks and measures of eye movement control. M.Sc. Thesis, Queen’s University, Kingston, ... -
Does Proteasome Inhibition Produce REM Sleep Behaviour Disorder Leading to Parkinson’s Disease? Examining a Progressive Model of Parkinson’s Disease
(2010-04-28)A recent model of Parkinson’s disease (PD) suggests that the neuropathological, behavioural and cognitive symptoms progress in stages. There is substantial evidence for a prodromal stage of PD, during which time pre-motor ... -
Local invariants for biological motion perception
(2010-07-21)Observers can retrieve the facing direction of a walker from point-light displays that are devoid of structure-from-motion information and retain solely local motion signals. This ability is orientation-dependent and ... -
A Mild Dementia Knowledge Transfer Program to improve knowledge and confidence in primary care: an exploratory study
(2010-07-27)Patients with dementia are often unaware of their disease and do not seek medical attention; thus, health care providers must shift to "active detection" to identify at-risk patients early. No previous studies have focused ... -
The combined effects of sensory and non-sensory variables on saccade selection processes in visual search
(2010-08-06)Decisions are based on multiple sources of information. For example, sensory information encoding environmental features may be combined with prior experience to bias judgements in visual behaviour. With the goal of ... -
Functional Magnetic Resonance Imaging of Peripheral Neuropathic Pain in the Spinal Cord and Brainstem
(2010-08-06)To date, most studies investigating the neural signature of pain in humans have focused on the brain, and those studies concerned with more caudal areas (such as the spinal cord (SC) or brainstem) have used only experimental ... -
Saccadic eye movement tasks assess central nervous system dysfunction and cognitive improvements in children with fetal alcohol spectrum disorders
(2010-08-17)Background: The central nervous system (CNS) dysfunction resulting from prenatal alcohol exposure (PAE) is the most debilitating aspect of fetal alcohol spectrum disorders (FASDs). Affected children exhibit numerous cognitive ... -
Improved Methods for Motion-Compensating and Event-Related Spinal Functional Magnetic Resonance Imaging (fMRI)
(2010-08-24)Functional magnetic resonance imaging (fMRI) has become a widely used technique for non-invasive brain mapping, and methods have now evolved to allow fMRI of the spinal cord (spinal fMRI) as well. With the goal of improving ... -
A candidate gene analysis of response to citalopram and escitalopram treatment in patients with major depressive disorder and generalized anxiety disorder
(2010-08-31)Objective: To determine whether genotype at the catechol-O-methyltransferase rs4680, dopamine D2 receptor rs1800497, serotonin receptor 1A rs6295 or serotonin transporter 5-HTTLPR single nucleotide polymorphisms is ... -
Post-Weaning Social Isolation and Subchronic NMDA Glutamate Receptor Blockade: Effects on Locomotor Activity and GABA Signalling in the Rat
(2010-09-01)The etiology and pathophysiology of schizophrenia are poorly understood, although increasing evidence suggests an important role for altered GABA neurotransmission. Animal models of schizophrenic symptoms include administration ... -
Sensory-motor deficits in children with Fetal Alcohol Spectrum Disorders assessed using a robotic virtual reality platform
(2010-09-02)Maternal consumption of alcohol during pregnancy can induce a range of behavioral and cognitive deficits in offspring, which are collectively termed Fetal Alcohol Spectrum Disorders (FASD). There are significant delays ...