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dc.contributor.authorBest, Mike
dc.contributor.otherQueen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.))en
dc.date.accessioned2019-04-22T19:48:02Z
dc.date.available2019-04-22T19:48:02Z
dc.identifier.urihttp://hdl.handle.net/1974/26097
dc.description.abstractCognitive remediation is an efficacious treatment for schizophrenia that focuses on enhancing neurocognitive abilities and improving community functioning. However, there is currently no gold-standard cognitive remediation therapy and different approaches have produced varying results on cognitive and functional outcomes. One of the major barriers preventing cognitive remediation from being recommended in treatment guidelines has been limited generalization of cognitive improvement to functional improvement. Although results have been inconsistent, executive functioning may be more closely related to community functioning than other domains of neurocognition. The objective of the current dissertation was to examine the efficacy of cognitive training that specifically targets executive functioning for individuals with schizophrenia-spectrum disorders. In Chapter 2 data are presented from a randomized, double blind trial examining a brief two-week executive functioning intervention compared to a sham training condition. Compared to sham training, executive training significantly improved EEG alpha and theta band synchronization during working memory tasks, and neuropsychological measures of working memory and executive functioning. In Chapter 3 data are presented from a randomized, double-blind trial examining brief executive function training compared to training of perceptual abilities on measures of neurophysiology, neurocognition, and functioning. Perceptual training improved the EEG mismatch negativity more than executive training immediately post-treatment however, the effect did not persist 12-weeks post-treatment. At 12-week follow-up, executive training significantly improved EEG theta power, neurocognition, functional competence, and case manager rated community functioning to a greater extent than perceptual training. Executive training may be a more efficient cognitive enhancing treatment than other cognitive remediation techniques, and treatment effects generalize to community functioning better than alternative cognitive training approaches.en_US
dc.language.isoenen_US
dc.relation.ispartofseriesCanadian thesesen
dc.rightsQueen's University's Thesis/Dissertation Non-Exclusive License for Deposit to QSpace and Library and Archives Canadaen
dc.rightsProQuest PhD and Master's Theses International Dissemination Agreementen
dc.rightsIntellectual Property Guidelines at Queen's Universityen
dc.rightsCopying and Preserving Your Thesisen
dc.rightsThis publication is made available by the authority of the copyright owner solely for the purpose of private study and research and may not be copied or reproduced except as permitted by the copyright laws without written authority from the copyright owner.en
dc.subjectschizophreniaen_US
dc.subjectpsychosisen_US
dc.subjectcognitive remediationen_US
dc.subjectfunctioningen_US
dc.subjectEEGen_US
dc.subjectcognitive trainingen_US
dc.titleThe BEST Trials: Examining Brief Executive Skills Training for Schizophrenia-Spectrum Disordersen_US
dc.typethesisen
dc.description.degreeDoctor of Philosophyen_US
dc.contributor.supervisorBowie, Christopher
dc.contributor.departmentPsychologyen_US


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