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dc.contributor.authorTadayyon, Hadien
dc.date2010-07-13 16:41:52.223
dc.date.accessioned2010-07-13T20:57:14Z
dc.date.available2010-07-13T20:57:14Z
dc.date.issued2010-07-13T20:57:14Z
dc.identifier.urihttp://hdl.handle.net/1974/5926
dc.descriptionThesis (Master, Electrical & Computer Engineering) -- Queen's University, 2010-07-13 16:41:52.223en
dc.description.abstractMRI-guided prostate needle biopsy requires compensation for organ motion between target planning and needle placement. Two questions are studied and answered in this work: is rigid registration sufficient in tracking the targets with a maximum error of 3 mm (smaller than average prostate tumor size) and how many intra-operative slices are required to obtain this accuracy? We developed rigid and deformable multislice- to-volume registration algorithms for tracking the biopsy targets within the prostate. Three orthogonal plus additional transverse intra-operative slices were acquired in the approximate center of the prostate and registered with a high-resolution target planning volume. Simulated intra-operative data, phantom data, and MRI-guided robotic prostate biopsy data were used to assess tracking accuracy. Registration tests on simulated intra-operative data with 3, 4, and 5 slices were performed to evaluate the effect on registration error and time. Results: Using three orthogonal slices pro- vides sufficient accuracy. Convergence test results on phantom images demonstrated 100% success rate for initial misalignment of 5mm. Average registration errors for the patient data were 2.55mm and 2.05mm for the rigid and deformable algorithms, respectively. The algorithm was able to capture rigid biopsy target displacements of maximum 8mm and non-rigid displacements of maximum 1.5mm. Rigid tracking appears to be promising. Deformable registration does not seem warranted.en
dc.language.isoengen
dc.relation.ispartofseriesCanadian thesesen
dc.rightsThis publication is made available by the authority of the copyright owner solely for the purpose of private study and research and may not be copied or reproduced except as permitted by the copyright laws without written authority from the copyright owner.en
dc.subjectProstateen
dc.subjectMotion Trackingen
dc.subjectMRIen
dc.subjectSlice-to-Volume Registrationen
dc.titleMRI-Guided Prostate Motion Tracking using Multislice-to-Volume Registrationen
dc.typethesisen
dc.description.degreeM.A.Sc.en
dc.contributor.supervisorFichtinger, Gaboren
dc.contributor.departmentElectrical and Computer Engineeringen
dc.degree.grantorQueen's University at Kingstonen


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