Browsing Department of Biology Graduate Theses by Title
Now showing items 304-323 of 331
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Targeted over-expression of hsp22 and the maintenance of locomotor activity of third instar larvae of Drosophila melanogaster at high temperatures
(2007-10-02)Hsp22 has been implicated in stress tolerance and longevity in various organisms though its role in Drosophila melanogaster larval thermal tolerance has not yet been investigated. I undertook this project to determine if ... -
Temperature Modulation of the Effects of Repetitive Anoxia on Potassium Homeostasis in the Brain of Drosophila melanogaster
(2012-01-30)Oxygen can be limited at the environmental (e.g. flood-prone burrows) or cellular (e.g. stroke, heart attack) levels. O2 deprivation in nervous tissue depolarizes cell membranes, incrementing extracellular potassium ... -
Testing the role of Baja California generating biodiversity: A test case characterizing the population genetic structure of Cassin's auklet (Ptychoramphus aleuticus)
(2012-09-28)Characterizing the population genetic structure of a species can provide insight into isolating effects of local adaptation and genetic drift, and homogenizing effects of gene flow. The relative interplay between gene flow ... -
Tetrahydrofuran Hydrate Inhibitors: Ice-Associating Bacteria and Proteins
(2009-03-31)Ice-associating proteins (IAPs) are proteins that interact directly with ice crystals, either by offering a site for nucleation, i.e. ice nucleating proteins (INPs), or by binding to nascent crystals to prevent addition ... -
Thinking outside the lake: Multiple scales of amphipod recovery
(2014-02-07)Tracking recovery in disturbed environments requires the consideration of many spatial and temporal scales. A sensitive indicator organism, Hyalella azteca, was used to assess lake recovery at multiple scales in the region ... -
Timing and Mechanism of Sepsis-Induced Delayed Gastric Emptying in a Novel Mouse Model
(2012-05-09)Sepsis-induced delayed gastric emptying is a significant clinical problem for patients in intensive care units worldwide. A series of studies were carried out to examine the nature and mechanisms of sepsis-induced delayed ... -
Tissue Specific Functions and Regulation of DAF-18/PTEN
(2015-01-15)The insulin signaling antagonist daf-18/PTEN is known to play various roles in the response of C. elegans to starvation. While daf-18’s roles in promoting dauer formation are well understood, the extent of its roles in L1 ... -
Tissue-specific transcriptional regulation of monocarboxylate transporters (MCTs) during short-term hypoxia in zebrafish (Danio rerio)
(2009-08-26)Monocarboxylate transporters (MCTs) have been shown to be important in regulating metabolism during hypoxia in mammals. However, the role of MCTs in hypoxic survival in lower vertebrates is currently unclear. The goal ... -
Towards a sustainable Arctic fishery: Population genomics of lake whitefish in a hybrid species complex
Genetic variation is an important predictor of population persistence under changing or stressful environmental conditions. Consequently, efforts to preserve genetic variation by identifying genetically distinct populations ... -
Towards an Understanding of Ice and Hydrate Adsorption by an Antifreeze Protein from Lolium Perenne
(2015-09-03)Lolium perenne (Lp), the perennial ryegrass, produces an antifreeze protein (AFP) when seasonal temperatures and levels of available sunlight drop in the autumn. This protein, along with other low-temperature induced stress ... -
Towards the Development of Transgenic Reporter Lines for Assessing and Characterizing a LAC-Regulated UAS-GAL4 System
(2015-05-20)I designed and prepared the components of an inducible gene expression system based on the mouse lac system to address limitations in conventional Drosophila melanogaster inducible gene expression systems that preclude ... -
The toxicity of alkyl-chrysenes and benz[a]anthracenes to embryonic fish
(2014-01-13)Alkylated polycyclic aromatic hydrocarbons (alkyl-PAHs) are major constituents of crude oil, and the 3-5 ringed alkyl-PAHs have been identified as the main components chronically toxic to fish. While chysene homologues ... -
Toxicity of Chemically Dispersed Crude Oil to Early Life Stages of Atlantic Herring (Clupea Harengus)
(2009-04-28)To minimize the damage caused by oil spills, responders may chemically disperse floating oil into the underlying water before it contacts shorelines and wildlife. Quantifying this strategy’s net ecological and commercial ... -
Toxicity of Chemically Dispersed Crude Oil to Herring Embryos
(2011-05-06)The use of chemicals to disperse oil spills raises concerns for organisms living below the surface of the water. While decreasing the surface area of the slick, chemical dispersants increase the amount of oil in the water ... -
Tracking Long-Term Holocene Climate Trends in Lake 239 (Experimental Lakes Area, NW Ontario) Using Diatoms, Pollen, and Charcoal
(2010-07-15)The boreal forest region of Canada is climatically sensitive and may be impacted by anthropogenic-induced climatic changes. The results of this multi-proxy paleolimnological study contribute detailed information on changes ... -
Transcriptional Response of Bioenergetic Genes to Exercise
(2015-12-10)Transcriptional responses to stressors are typically measured as changes in mRNA levels, despite a broad awareness that transcript levels do not equate to transcription rates. I was able to use goldfish (Carassius auratus) ... -
Unraveling the Function of Bacterial-Type Phosphoenolpyruvate Carboxylase in Vascular Plants
(2016-10-03)Two distinct phosphoenolpyruvate carboxylase (PEPC) isozymes occur in vascular plants and green algae: plant-type PEPC (PTPC) and bacterial-type PEPC (BTPC). PTPC polypeptides typically form a tightly regulated cytosolic ... -
The Use of Historical Data to Describe Changes in Fish Communities Over Time
(2015-10-06)This thesis, comprised of two studies, investigates the use of historical data to describe changes in fish communities over time. Identifying changes in fish community is important for the conservation of biodiversity. The ... -
Using Insect Model Systems to Study Mechanisms of Spreading Depression
(2015-12-14)Spreading depression (SD) occurs as a slowly propagating wave of neural inactivity and plays an important role in both the vertebrate and invertebrate CNS. Mammalian SD is associated with human pathologies such as migraine, ... -
Using Paleolimnology to Reconstruct Past Environments of Lakes Affected by Direct Anthropogenic Activities
(2015-07-29)Although the magnitude of recent anthropogenic environmental change is unprecedented, humans have been leaving measurable footprints on the landscape prior to the era of industrialization. This thesis examines the long-term ...