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Tissue Specific Functions and Regulation of DAF-18/PTEN
The insulin signaling antagonist daf-18/PTEN is known to play various roles in the response of C. elegans to starvation. While daf-18’s roles in promoting dauer formation are well understood, the extent of its roles in L1 ...
Exploring the Functional Significance of the Caenorhabditis elegans VAB-1 Eph RTK and DAF-18/PTEN Tumour Suppressor Interaction
The Caenorhabditis elegans Eph RTK, VAB-1, has known roles in neuronal and epidermal morphogenesis as well as oocyte maturation through interaction with its ephrin ligands. In humans, Eph receptors are involved in nervous ...