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Characterization of Signal Transduction Pathways Required for Starvation Longevity in the Model Nematode Caenorhabditis Elegans
Growth and development is controlled by specific sets of gene products (proteins and RNAs), forming metabolic and developmental pathways. Mutations in these genes can result in abnormal growth of cells, leading to diseases ...
Tissue Specific Functions and Regulation of DAF-18/PTEN
The insulin signaling antagonist daf-18/PTEN is known to play various roles in the response of C. elegans to starvation. While daf-18’s roles in promoting dauer formation are well understood, the extent of its roles in L1 ...