Monocarboxylate transporters (MCTs) have been shown to be important in regulating metabolism during hypoxia in mammals. However, the role of MCTs in hypoxic survival in lower vertebrates is currently unclear. The goal ...

Several genes involved in the regulation of apoptosis can influence longevity. Although observations in several different systems imply that apoptosis and aging are closely linked, the relationship between the two remains ...

The Caenorhabditis elegans Eph RTK, VAB-1, has known roles in neuronal and epidermal morphogenesis as well as oocyte maturation through interaction with its ephrin ligands. In humans, Eph receptors are involved in nervous ...

A recent hypothesis for explaining blue-green eggs in birds suggests that they may be a sexually selected signal of female (and thus nestling) quality that males use to make parental investment decisions. Although this ...

Freshwater ecosystems face unprecedented levels of human-induced stresses and it is expected that the invasion of non-indigenous species will cause the greatest loss of biodiversity in lakes and rivers worldwide. Bythotrephes ...

In multicellular organisms, apoptosis plays an important role in maintaining cellular homeostasis and removing damaged cells that present a threat to the integrity of the organism. Several lines of evidence suggest that ...

Cancer cells have the ability to survive when oxygen is limiting, and upregulate the pathway of fatty acid synthesis, owing in part to alterations in their metabolism. I compared the metabolic phenotypes of the prostate ...

Widespread abandonment of agricultural land has occurred in northeastern North America over the past two centuries. Soil carbon often increases as sites naturally regenerate towards perennial grasslands or forests. ...

Acid phosphatases (APases; E.C. 3.1.3.2) catalyze the hydrolysis of phosphate (Pi) from Pi monoesters and anhydrides within the acidic pH range. Induction of intracellular and secreted purple acid phosphatases (PAPs) is a ...

Bythotrephes longimanus, a predatory exotic cladoceran, has spread rapidly to numerous lakes through the Laurentian Great Lakes region of Ontario and North America. Post-invaded lakes are known to have reduced zooplankton ...