Search
Now showing items 1-6 of 6
Dopamine D1-Like, D2 and D3 Receptor Subtypes in Catalepsy Sensitization and Conditioning in Rats: Implications for Motor Function, Motivation and Learning
(2012-08-13)
The behavioral effects of drugs that act on the brain’s dopamine (DA) system change with repeated exposure to the drug. Antipsychotic drugs, that block DA receptors, produce progressively greater effects on behavior with ...
The Distribution of Serotonergic, Noradrenergic and Dopaminergic Synapses on Flexor Motoneurons
(2011-09-29)
Serotonin (5-HT) and noradrenalin (NA) increase persistent inward currents mediated by sodium and calcium channels on the dendrites of motoneurons. The ability of 5-HT and NA to modulate these channels depends on the ...
Study of the Role of the Bed Nucleus of the Stria Termialis D1- and D2-Like Dopamine Receptors in Cocaine Self-Administering Rats
(2015-11-04)
Previous studies have suggested the importance of the bed nucleus of the stria terminalis (BST) in modulating drug seeking behaviors. With heavy reciprocal projections from the BST to various dopamine rich areas (ventral ...
Haloperidol-Environment Interaction Modulates Expression of c-Fos Proteins in the Basal Ganglia in Rats
(2015-12-16)
Inverse incentive learning is the loss by stimuli of their ability to elicit approach and other responses. This has been shown in the horizontal bar test. Rats in the Paired group (n = 10) were injected with haloperidol ...
Inhibition of Wnt Signalling Dose-Dependently Impairs the Acquisition and Expression of Amphetamine-Induced Conditioned Place Preference in Rats
The mechanisms by which dopaminergic neurotransmission in the nucleus accumbens (NAc) is involved in incentive learning produced by rewarding stimuli remain unclear. Recently, Wnt signalling has been implicated in synaptic ...
Double Dissociation of the Effects of Haloperidol and the Dopamine D3 Receptor-Specific Antagonist ABT-127 on Acquisition vs. Expression of Cocaine Conditioned Activity
(2007-09-19)
The psychostimulant effects of cocaine can be associated with environmental stimuli and thus can be easily conditioned in a laboratory setting. In rats, both behavioural stimulant and reinforcing effects of cocaine have ...