Functional MRI of the human spinal cord and brainstem has tremendous potential to enhance our basic understanding of healthy subcortical function, and impact our ability to accurately diagnose and treat injury and disease. ...

Functional magnetic resonance imaging (fMRI) studies performed to date have focused on brain structures rostral to the thalamus, although the first level of sensory information and pain transmission occurs at the spinal ...

The experience of pain is a highly complex and personal experience, characterized by tremendous inter-individual variability. Pain perception can differ substantially across individuals due to many factors such as age, ...

When one noxious stimulus is coupled with a second noxious stimulus applied to a remote region of the body relative to the first stimulus, the perception of pain is reduced. This phenomenon is termed conditioned pain ...

Altered sexual function is one of the most devastating consequences of spinal cord trauma (SCT). Despite this fact, current knowledge of the neural circuitry regulating sexual response in the spinal cord (SC) in healthy ...

Many studies of ‘executive control’ have focused on the prefrontal cortex (PFC), which contains the neuronal functional properties, modulatory neurotransmitters, and network connections with sensory and motor regions to ...

To date, most studies investigating the neural signature of pain in humans have focused on the brain, and those studies concerned with more caudal areas (such as the spinal cord (SC) or brainstem) have used only experimental ...

We investigated age-related differences in neural activation associated with recognition of familiar melodies, a process that requires retrieval from musical semantic memory and leads to a feeling of familiarity. We used ...

The most common and natural human behaviours are often the most computationally difficult to understand. This is especially true of spoken language comprehension considering the acoustic ambiguities inherent in a speech ...

Patients with Amyotrophic lateral sclerosis (ALS) often experience cognitive impairment that accompanies degeneration of the motor system. A valuable tool for assessing cognitive control over behaviour is the antisaccade ...