Browsing Public Health Sciences, Department of by Title
Now showing items 27-46 of 209
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Cellulitis: Comorbidities as a determinant of hospital length-of-stay
(2009-11-19)Background: Cellulitis is a common skin and soft-tissue infection that often recurs in some patients. Patients with presenting comorbid conditions may require hospitalization which increases the cost of treatment. However, ... -
Cholinesterase Inhibitors: A population-based assessment of resource utilization for patients with Alzheimer's dementia in Ontario
(2011-11-02)Background: Dementia leads to progressive cognitive and functional decline. Population aging is a concern, and the healthcare system must refocus its limited resources to keep up with service demands. Three cholinesterase ... -
Clinical validation of the Walking Impairment Questionnaire in patients with peripheral arterial disease: defining high and low walking performance values
(2011-08-25)Objective: The validity of the Walking Impairment Questionnaire (WIQ) as a clinical tool for use by clinicians in the conservative management of patients with peripheral arterial disease (PAD) has not been well established. ... -
Colorectal cancer diagnostic pathways in Ontario
Purpose: The purpose of this study was to differentiate diagnostic pathways in colorectal cancer in Ontario through the development of a pathway categorization scheme, and evaluate the patient-, disease-, system-related ... -
Combining Biomarkers and Clinicopathologic Factors for Prediction of Response to Adjuvant Chemotherapy for Breast Cancer: Cox Model and Support Vector Machine (SVM) Methods
(2010-04-27)Background: Breast cancer is a complex disease, both phenotypically and etiologically. Accordingly, the responses to various treatments in the adjuvant setting among individuals vary considerably. There is a demand for ... -
Communicating Results of New Genomic Tests to Physicians
(2009-05-07)Background: New genomic tests are being developed to predict an individual’s risk of cancer recurrence by analyzing the expression of multiple genes. However, it is unclear how to report the test results so that they would ... -
Comparing the Responsiveness of two Health-Related Quality of Life Instruments in a Phase III Randomized Clinical Trial of Men With Prostate Cancer (NCIC CTG PR.3): the EORTC QLQ-C30+3 With PR17 Trial Specific Checklist Versus the FACT-P
(2015-04-30)Background: The EORTC QLQ-C30 and the FACT are two commonly used Health-Related Quality of Life (HRQL) instruments in cancer clinical trials, but there is limited data comparing them. The NCIC CTG PR.3 clinical trial ... -
Comparison of a Newly Proposed Staging System with 7th Edition AJCC/UICC System for Surgically Resected Patients with Intrahepatic Cholangiocarcinoma
Background: Intrahepatic cholangiocarcinoma (IHCC) is a rare but lethal primary liver cancer. Debate exists about whether tumor size should be considered in disease staging. This study aimed to examine the association ... -
The Compositional associations of time spent in sleep, sedentary behaviour and physical activity with all-cause mortality
INTRODUCTION: Daily time spent in sleep, sedentary behaviour (SED), light intensity physical activity (LIPA), and moderate-to-vigorous intensity physical activity (MVPA) are compositional, co-dependent variables. The ... -
The Compositional Effects of Time Spent in Sleep, Sedentary Behaviour and Physical Activity on Obesity in Children
Abstract Purpose Physical activity, sedentary behaviour (SB) and sleep have traditionally been studied as independent behaviours and not as co-dependent behaviours that are compositional in nature. This study used ... -
Coronary Angiography and Neurologically Intact Survival in Out-of-Hospital Cardiac Arrest Patients with Return of Spontaneous Circulation
(2015-10-03)Introduction: Acute Coronary Syndrome (ACS) is prevalent in out-of-hospital cardiac arrest (OHCA) patients but only a minority receives coronary angiography. Also, evidence for the effectiveness of coronary angiography in ... -
Describing the Effectiveness of Palliative Gemcitabine in Patients With Advanced Pancreatic Cancer Treated at the Regional Cancer Centres of Ontario
(2012-08-08)Background: Palliative gemcitabine has been shown to prevent the deterioration of well-being and to prolong survival of patients with pancreatic cancer in phase III randomized controlled trials (RCTs). It is unknown whether ... -
Determinants and methods of assessment of melatonin levels among rotating shift nurses
(2008-06-30)Background: Long-term night shift work has been associated with multiple cancer sites, including breast, prostate, colon and endometrial. The mechanism for this effect is hypothesized to include the hormone melatonin; where ... -
Determinants of Cervical Cancer Screening in the Kilimanjaro Region of Tanzania
(2013-10-02)Background: Cervical cancer is a leading cause of death in Tanzanian women, with annual age-standardized mortality of 38 per 100,000. While organized screening programs have minimized cervical cancer rates in the developed ... -
Determinants of non-uptake of the quadrivalent HPV vaccine; The Ontario Grade 8 HPV Vaccine Cohort Study
(2013-02-04)Background: In 2007, the Canadian federal budget provided $300 million over three years to the provinces and territories to implement publicly-funded HPV immunization programs. Current estimates indicate that HPV vaccine ... -
Development and Psychometric Evaluation of the Post-Secondary Student Stressors Index
Background: Over the past several years, reports of excessive stress and symptoms of languishing mental health have been increasingly reported among samples of Canadian post-secondary students. Chronic stress is highly ... -
Development of a Questionnaire for Measuring the Quality of Personal Care in Patients Undergoing Radiotherapy for Prostate Cancer
(2010-12-17)Background: Quality of patient care includes both technical and non-technical elements of care, referred to as personal care. Previous work has focused on assessing the quality of technical care in prostate cancer radiotherapy, ... -
The Diagnostic Interval of Colorectal Cancer Patients in Ontario by Degree of Rurality
(2015-10-03)Background: Wait times while moving through the cancer diagnostic process are a public health concern. Rural populations may experience more challenges in accessing cancer care, which could translate into a longer diagnostic ... -
Dietary Patterns and Risk of Diabetes and Mortality: Impact of Cardiorespiratory Fitness
(2009-07-08)The primary objective of this study was to assess the relationship between dietary patterns with diabetes and mortality risk from all-cause and cardiovascular disease while controlling for the confounding effects of fitness. ... -
The differential impact of oxytocin receptor (OXTR) genotypes on the risk of autism spectrum disorder (ASD) and resulting social communication deficits
(2016-08-15)Background: Autism spectrum disorder (ASD) is multifactorial and is likely the result of complex interactions between multiple environmental and genetic factors. Recently, it has been suggested that each symptom cluster ...