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The association between usual health care utilization and stage at diagnosis in laryngeal cancer
(2012-04-26)
Background: A significant number of laryngeal cancer patients are diagnosed with advanced-stage disease. Since stage at diagnosis is an important prognostic factor, it is necessary to understand the characteristics of ...
Assessing the Risk for Autoimmune Disorders Following Use of the Quadrivalent Human Papillomavirus Vaccine: the Ontario Grade 8 HPV Vaccine Cohort Study
(2014-04-24)
Introduction: In 2007 Ontario implemented a grade 8 quadrivalent human papillomavirus (qHPV) vaccination program targeting the virus that causes cervical cancer. Despite being 6 years post-implementation, few post-licensure ...
Recreational use of prescription medications among Canadian young people: Identifying demographic and geographic disparities
(2013-10-02)
BACKGROUND: The nonmedical use of prescription medications among young people has escalated substantially in recent years. Certain subgroups of adolescents are at greater risk than others, including rural youth, however ...
Bi-directional Association between Sleep and Outdoor Active Play among 10- to 13-year-olds
Purpose: The purpose of this study was to investigate whether there is a bi-directional relationship between sleep characteristics (time in bed, sleep duration, sleep efficiency) and outdoor active play (OAP) within children. ...
The Risk of Serious Respiratory-Related Events Following Immunization with the Quadrivalent Human Papillomavirus (qHPV) Vaccine: The Ontario Grade 8 HPV Vaccine Cohort Study
(2014-04-17)
Background: The qHPV vaccine has the potential to significantly reduce the burden of HPV-related diseases, including cervical cancer. However, a recent systematic review of clinical trials has suggested that the risk of ...
Clinical validation of the Walking Impairment Questionnaire in patients with peripheral arterial disease: defining high and low walking performance values
(2011-08-25)
Objective: The validity of the Walking Impairment Questionnaire (WIQ) as a clinical tool for use by clinicians in the conservative management of patients with peripheral arterial disease (PAD) has not been well established. ...
An Examination of Canadian Family Physicians’ Knowledge and Practice Patterns Regarding Breast Cancer Prevention
(2009-09-26)
Family physician (FP) knowledge regarding breast cancer risk assessment and prevention strategies such as chemoprevention are important in ensuring that women at high risk for breast cancer are identified and receive proper ...
Physical mobility and aging in intellectual disability
(2007-09-14)
Background: The growing population of older adults with intellectual disabilities is likely to experience secondary disabilities that affect well-being. Despite the established importance of mobility in the general ...
Factors Associated With Worsening Menopause-Specific Health-Related Quality of Life and Treatment Discontinuation in a Breast Cancer Chemoprevention Trial
(2015-09-10)
Background: The Mammary Prevention.3 (MAP.3) randomized placebo-controlled trial evaluating exemestane for breast cancer prevention demonstrated a 65% relative reduction in invasive breast cancer incidence. Up to 50% of ...
Using Population Health Surveys to Measure the Use of Services and the Prevalence of Psychiatric and/or Behavioural Conditions in Individuals with an Intellectual Disability
(2009-10-30)
Background: Compared to the general population, individuals with intellectual disabilities have a higher prevalence of health problems, including psychiatric and/or behavioural conditions (dual diagnosis). Research suggests ...