Browsing Department of Public Health Sciences Graduate Theses by Publish Date
Now showing items 1-20 of 211
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Effect of computer decision support system on antibiotic utilization in a complex continuing care and rehabilitation hospital
(2007-07-18)Background: Considerable amount of inappropriate antibiotic utilization has been observed in both acute and non-acute care hospitals. Literature has shown that strategies such as an order entry (OE) and computer decision ... -
Validation of quality indicators for radical prostatectomy
(2007-08-29)BACKGROUND: Radical prostatectomy is the surgical procedure performed on men with clinically localized prostate cancer. In recent years, radical prostatectomy quality indicators have been recommended, but the feasibility ... -
Physical mobility and aging in intellectual disability
(2007-09-14)Background: The growing population of older adults with intellectual disabilities is likely to experience secondary disabilities that affect well-being. Despite the established importance of mobility in the general ... -
The Effect of Antidepressants on Cardiovascular Morbidity and Mortality: A Population-based Cohort Study
(2007-09-17)Background: Antidepressants such as selective serotonin reuptake inhibitors (SSRIs) and venlafaxine have the potential to exert beneficial effects on the heart via serotonin mediated antiplatelet activity. However, ... -
Investigation into the relationship between Physical Activity and Homocysteine
(2007-09-26)Background: A beneficial effect of physical activity on the risk of cancer at several sites has been consistently observed. Biologic mechanisms that may underlie this relationship are not well understood. A potential ... -
The food retail environment surrounding Canadian schools and its impact on overweight and obesity
(2007-10-01)Background: The prevalence of overweight and obesity in Canadian youth has increased considerably over the past few decades. In spite of considerable efforts, individual-level behavioural modification strategies have not ... -
A study of prehospital trauma care in Ontario
(2007-12-14)Objectives: 1. To describe variations in major trauma between rural and urban residents of Ontario in terms of external causes, severities, prehospital care and clinical outcomes. 2. To determine whether prehospital ... -
Selective serotonin reuptake inhibitors (SSRIs) and breast cancer : a record linkage study
(2008-01-09)Evidence suggests that selective serotonin reuptake inhibitors (SSRIs, a class of antidepressant medications) may contribute to increased breast cancer risk by stimulating the secretion of prolactin, a potential tumour ... -
School and neighbourhood recreational environments and their impact on physical activity participation among Canadian youth
(2008-05-27)Background: Less than half of Canadian youth meet recommended levels of physical activity. This is of concern given the health burden associated with physical inactivity. With the limited success of physical activity ... -
Determinants and methods of assessment of melatonin levels among rotating shift nurses
(2008-06-30)Background: Long-term night shift work has been associated with multiple cancer sites, including breast, prostate, colon and endometrial. The mechanism for this effect is hypothesized to include the hormone melatonin; where ... -
Identifying responders to melphalan and dexamethasone for newly diagnosed multiple myeloma patients
(2008-07-22)Background: MY7 clinical trial compared dexamethasone plus melphalan (MD) vs. prednisone plus melphalan (MP) in multiple myeloma treatment and found no statistically significant difference in overall survival (OS) between ... -
Influence of polymorphisms in the thymidylate synthase gene on plasma homocysteine concentration
(2008-08-22)Background: Significant interest in homocysteine exists due to its established role in embryogenesis, cardiovascular disease and neurotoxicity. This research investigates total plasma homocysteine in the context of ... -
Estimating the burden of occupational bladder cancer in Ontario using the CAREX Canada database
(2008-09-04)Objective: This study attempts to estimate the proportion of incident cases of bladder cancer in Ontario, Canada that is due to exposure to occupational carcinogens. Methods: The population attributable risk approach is ... -
Relationships between income inequality and health: an ecological Canadian study.
(2008-09-17)Abstract Background: Many studies have demonstrated that health is a function of relative and not absolute income within populations. Canadian studies are not conclusive. There is a need for further investigation ... -
Forensic psychiatry and criminal responsibility in Santiago, Chile
(2008-09-23)Mental disorders are among the most prevalent of chronic diseases, and high rates of these disorders have been consistently found in jails and prisons. This study was a retrospective case series that described the population ... -
A pilot project to investigate a novel computerized concussion assessment tool for use in the emergency department and other outpatient settings
(2008-09-24)Background: There is currently no standard method of diagnosing the presence or severity of concussion in acute primary care settings. This pilot project is part of a larger study to develop a Computerized Concussion ... -
Effect of Alcohol Consumption and Alcohol Dehydrogenase 1C (ADH1C) Polymorphisms on Total Plasma Homocysteine Levels
(2008-09-27)BACKGROUND: Evidence supports that an elevated level of total plasma homocysteine (tHcy) signifies a breakdown in the methionine-homocysteine cycle. This may result in folate deficiency, DNA methylation and oxidative ... -
Prevalence and associations of Coronary Artery Calcification in Patients with Stages 3-5 Chronic Kidney Disease without Cardiovascular Disease
(2009-04-22)Background: Coronary artery calcification (CAC) is common in chronic kidney disease (CKD) patients, and is demonstrable in fifty percent of incident dialysis patients. Therefore, the process of CAC initiation likely occurs ... -
Communicating Results of New Genomic Tests to Physicians
(2009-05-07)Background: New genomic tests are being developed to predict an individual’s risk of cancer recurrence by analyzing the expression of multiple genes. However, it is unclear how to report the test results so that they would ... -
Dietary Patterns and Risk of Diabetes and Mortality: Impact of Cardiorespiratory Fitness
(2009-07-08)The primary objective of this study was to assess the relationship between dietary patterns with diabetes and mortality risk from all-cause and cardiovascular disease while controlling for the confounding effects of fitness. ...