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Effect of Alcohol Consumption and Alcohol Dehydrogenase 1C (ADH1C) Polymorphisms on Total Plasma Homocysteine Levels
BACKGROUND: Evidence supports that an elevated level of total plasma homocysteine (tHcy) signifies a breakdown in the methionine-homocysteine cycle. This may result in folate deficiency, DNA methylation and oxidative ...
Established and suspected risk factors for breast cancer: A case-control study in Vancouver, BC and Kingston, ON
More than half of all cases of breast cancer occur among women without any known risk factors. More research is needed on suspected risk factors in order to refine current breast cancer screening tools. The objectives ...
The Influence of Alcohol Consumption, Smoking, and Physical Activity on Peripheral Blood Leukocyte Telomere Length
BACKGROUND: Telomeres are repetitive DNA sequences and associated proteins that cap the ends of chromosomes. Functional telomeres protect genetic information and maintain chromosomal stability. Critically short telomeres ...