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The Role of Phosphodiesterases in Cyclic Nucleotide Compartmentation Across Different Pathways in the Adult Rat Ventricular Myocyte
In cardiac myocytes, multiple receptor mediated signalling pathways converge on cyclic nucleotide production. These second messengers act to achieve changes in cellular function. Despite this, each signalling molecule ...
Electrophysiological Characterization of Sodium Currents in Adult Rat Cardiac Myocytes
The electrical heterogeneity of the heart has been recognized as an important feature of normal cardiac function. In cardiac myocytes, considerable electrophysiological differences in sodium channel currents have been ...
Modulation of Cardiac Myocyte Function by Reactive Oxygen Species
Previous investigations have demonstrated that reactive oxygen species such as hydrogen peroxide (H2O2) have the ability to alter electrophysiological and mechanical properties of rat ventricular cardiac myocytes. However, ...