Now showing items 1-6 of 6
The Effects of Hydrogen Sulfide on Neurons in the Nucleus of the Solitary Tract
Hydrogen sulfide (H2S) is a gasotransmitter that has recently been described to affect the membrane potential of neurons in a number of brain areas. Using whole cell patch-clamp electrophysiological techniques, I investigated ...
Investigating the contribution of the basal ganglia in the selective gating of saccade initiation
An important function of the brain is to inhibit irrelevant behaviors. This thesis examines the role of the basal ganglia in response suppression using saccadic eye movements as a model of behavior. We measured the activity ...
Evidence for effects of nesfatin-1, alpha-melanocyte stimulating hormone, and glucose on the excitability of individual neurons in the nucleus of the solitary tract
The nucleus of the solitary tract (NTS) is a medullary autonomic center with essential roles in the regulation of energy homeostasis. Understanding how the NTS contributes to the coordination of ingestive behaviors and ...
SFO Neurons are Glucose Responsive
Glucose is the primary metabolic signal reflecting the current energy state of the body. Glucose influences the excitability of neurons in the area postrema (AP), a circumventricular organ (CVO), prompting my interest in ...
Axotomized Spinal Commissural Interneurons of the Adult Feline: A study of axonal growth from dendrites and cut axons
Acquiring knowledge of the morphological, molecular, and functional changes that occur to neurons following axotomy is a key step for a comprehensive understanding of the nervous system and how it reacts to injury. ...
Role of Caveolin-3 in the Modulation of hERG Potassium Channel
The human ether-a-go-go-related gene (hERG) encodes the pore-forming subunit of the rapidly activating delayed rectifier potassium channel (IKr) that is important for cardiac repolarization. Previously, we have discovered ...