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Regulation of the Human Ether-à-Go-Go-Related Gene (hERG) Channel by RAB4 Through Neural Precursor Cell-Expressed Developmentally Downregulated Protein 4-2 (NEDD4-2)
The human ether-à-go-go-related gene (hERG) encodes the pore-forming α-subunits of the Kv11.1 channel that is responsible for the cardiac rapidly activating delayed rectifier K+ current (IKr), which plays a critical role ...
Febrile Temperature Facilitates Degradation of Human Ether-a-Go-Go-Related Gene (hERG) Channels
The human ether-a-go-go-related gene (hERG) encodes the α subunit of the rapidly activating delayed rectifier K+ channel (IKr), which plays an essential role in human cardiac repolarization. Dysfunction of hERG caused by ...
Scorpion Toxin BeKm-1 Prevents Low K+ Induced Internalization of Cell-Surface hERG Channels
The human ether-à-go-go related gene (hERG) encoded the pore forming subunit of a K+ channel that conducts an important current for the repolarization of the cardiac action potential. Dysfunction of the hERG channel leads ...